RESUMO
In the present work, 20 patients with salivary pleomorphic adenoma were recruited for FTIR spectroscopic measurement. These obtained FTIR spectra were analyzed and compared. It was found that there were significant differences in the spectral features of the skin covering normal salivary gland, pleomorphic adenoma, and carcinoma change of pleomorphic adenoma, such as the changes in peak position, band shape and relative intensity of the bands in the ranges of 1000-1800 cm(-1) and 2800-3000 cm(-1). Pathological diagnosis demonstrated that 2 of the 20 patients suffered actually carcinoma change of pleomorphic adenoma, which is in good agreement with the result of FTIR spectroscopicmeasurement. FTIR spectroscopic m ethodsuggested that pleomorphic adenoma is the intermediate between normal salivary gland and carcinoma change of pleomorphic adenoma.
Assuntos
Adenoma Pleomorfo/química , Neoplasias das Glândulas Salivares/química , Espectroscopia de Infravermelho com Transformada de Fourier/métodos , Adenoma Pleomorfo/diagnóstico , Adenoma Pleomorfo/patologia , Humanos , Neoplasias das Glândulas Salivares/diagnóstico , Neoplasias das Glândulas Salivares/patologiaRESUMO
In this paper, stained and unstained samples of oral tissues have been investigated using FT-microspectroscopy. The experimental results demonstrated that staining did not influence the characteristic features of the FTIR spectra of the oral tissues, thereby providing abundant opportunity of further understanding of the structural-spectral relationship of normal and malignant tissues.
