RESUMO
OBJECTIVE: To investigate the chemical constituents of Ligularia xanthotricha. METHOD: Silica gel column chromatography and preparative TLC were employed for the isolation and purification. The structures were identified on the basis of spectral data (IR, EI-MS, 1H-NMR, 13C-NMR, DEPT) and chemical evidence. RESULT: Seven compounds were isolated and identified as follows: lupeol (1), lupeol palmitate (2), 3, 28-dihydroxyl-lupeol (3), betulinic acid (4), taraxasterol (5), taraxasteryl palmitat (6) and taraxasteryl acetate(7). CONCLUSION: All the compounds were isolated from this plant for the first time.
Assuntos
Asteraceae/química , Triterpenos/química , Cromatografia em Gel , Cromatografia em Camada Fina , Espectroscopia de Ressonância Magnética , Estrutura Molecular , Triterpenos Pentacíclicos , Espectrometria de Massas por Ionização por Electrospray , Esteróis/química , Esteróis/isolamento & purificação , Triterpenos/isolamento & purificação , Ácido BetulínicoRESUMO
OBJECTIVE: To study the chemical constituents from Lamium maculatum var. kansuense. METHOD: The chemical constituents were isolated and repeatedly purified on silica gel column and the structures were elucidated by the NMR spectra and physico-chemical properties. RESULT: Six compounds were obtained and identified as polypodine B (I), 5-OH-8-epiloganin (II), shlanzhiside methyl ester (III), liriodendrin (IV), quercitroside (V), uridine (VI). CONCLUSION: Compound IV was found from genus Lamium for the first time and the rest of the compounds were found from Lamium maculatum var kansuense for the first time.
