White matter microsusceptibility changes in patients with hepatic encephalopathy.

We report a new radiological finding in two patients with hepatic encephalopathy. A new susceptibility-weighted (SWI) magnetic resonance imaging sequence revealed multiple bilateral microsusceptibility changes in the corpus callosum and white matter, while the conventional T1 and T2 weighted images were unremarkable. We postulate that the etiology of the microsusceptibility changes may be related to hepatic coagulopathy and other factors, such as impaired cerebral blood flow and brain edema.