[Cerebrospinal fluid prealbumins in children with subacute sclerosing panencephalitis]. / Prealbuminy plynu mózgowo-rdzeniowego u dzieci chorych na podostre stwardniajace zapalenie mozgu.

In the cerebrospinal fluid of 26 children with SSPE the levels of prealbumins and total proteins were determined and electrophoretic separation of proteins was done. The usefulness is discussed of the percent proportion of prealbumins in the cerebrospinal fluid as a criterion indicating damage to the blood-cerebrospinal fluid barrier with increased penetration of proteins in SSPE. It is concluded that in diseases in which biosynthesis occurs of proteins in the central nervous system the percent proportion of prealbumins fails to reflect the integrity of the brain-cerebrospinal fluid barrier.

[Mirror writing in a child]. / Pismo lustrzane u dziecka.

The authors analysed the causes of mirror writing and its evolution in a girl aged 7-9 years. Among the possible causes they consider changing lateralization of extremities, absence of evident predominance of a hemisphere, acquiring of this writing by exercise through imitation with the left hand of the writing movements performed by the right hand, and the possibility of microtrauma of the central nervous system. It is stressed that the mental development was normal and there were on features of developmental dyslexia.

Subacute sclerosing panencephalitis in twins.

Development of subacute sclerosing panencephalitis after measles has been observed in twins although the disease seems to be quite exceptional in members of the same family, and no report has been found on its occurrence in twins.

[Lysozyme concentration in the cerebrospinal fluid of children with epilepsy and subacute sclerosing encephalitis]. / Stezenie lizozymu w plynie mózgowo-rdzeniowym u dzieci chorych na padaczke oraz podostre stwardniajace zapalenie mózgu.

Lysozyme concentration in the cerebrospinal fluid was determined in 21 children with epilepsy and 22 children with subacute sclerosing panencephalitis. In most children in both groups the concentration of the enzyme was in the range of control values, but in the remaining children it was above the upper limit of these values. No correlation was demonstrated between lysozyme concentration and total protein level in the cerebrospinal fluid. The causes of raised values of cerebrospinal concentration in these children are discussed.

Prevalence of measles antibodies in patients with subacute sclerosing panencephalitis in Poland in the years 1971--1978.

Between 1971 and 1978, clinical centres in four provinces of Poland reported 107 cases of subacute sclerosing panencephalitis (SSPE). This series comprised 73.8% boys and 26.2% girls. Most children were aged 6--8 years, and 66% of them had had measles in the first two years of life. As compared with a control group the geometric means of the haemagglutination-inhibiting antibodies and neutralizing antibodies were between ten and twenty times higher in SSPE patients. Determinations of the levels of antibodies carried out several times during the disease showed a rise of the titres to values as high as 1 : 128,000 in the serum and 1 : 1,024 in the cerebrospinal fluid in some cases.

[Changes in cerebrospinal fluid protein concentration in children following surgery for cerebellar medulloblastoma]. / Zmiany stezenia bialka w plynie mózgowo-rdzeniowym u dzieci po operacji rdzeniaka mózdzku.

In 10 children after operations for cerebellar medulloblastoma treated with intrathecal injections of methotrexate changes were studied in the concentration of total protein in the cerebrospinal fluid and in different electrophoretic fractions of proteins. The investigations were begun 1 to 3 months after the operation and were continued usually at monthly time intervals. In each child considerable variations were observed in the concentration of total protein as well as in the proportions of protein electrophoretic fractions in the period of treatment lasting from 14 to 59 months after the operation. Significant individual variations were observed also in the level of total protein fractions pattern in the cerebrospinal fluid. Out of 116 electrophorograms in 42 the protein fraction pattern in the cerebrospinal fluid approached very much that found in patients with cerebellar medulloblastoma before the operation, with a significant rise in the proportion of albumins. The origin of cerebrospinal fluid proteins is discussed.