Screen-Printable Iontronic Pressure Sensor with Thermal Expansion Microspheres for Pulse Monitoring.

Constructing microstructures to improve the sensitivity of flexible pressure sensors is an effective approach. However, the preparation of microstructures usually involves inverted molds or subtractive manufacturing methods, which are difficult in large-scale (e.g., in screen printing) preparation. To solve this problem, we introduced thermally expandable microspheres for screen printing to fabricate flexible sensors. Thermally expandable microspheres can be constructed into microstructures by simple heating after printing, which simplifies the microstructure fabrication step. In addition, the added microspheres can also be used as ionic liquid reservoir materials to further increase the capacitance change and improve the sensitivity. The prepared sensors exhibited superior performance, including ultrahigh sensitivity (Smax = 49999.5 kPa-1) and wide detection range (0-350 kPa). Even after 30,000 cycles at a high pressure of 300 kPa and a low pressure of 30 kPa, the sensor showed minimal signal degradation, demonstrating long-term cycling stability. In order to verify the practical potential of the sensors, we performed human radial artery beat detection experiments using these sensors. The variations in the intensity of the 3D radial artery pulse wave can be observed very clearly, which is important for human health monitoring. The above demonstrates that our strategy can provide an effective approach for the large-scale preparation of high-performance flexible pressure sensors.

Progress in quantification of nicotine content and form distribution in electronic cigarette liquids and aerosols.

Each electronic cigarette (e-cigarette) is a battery-powered system which converts electronic cigarette liquids (e-liquids) into the inhalable phase by heating the solution when it is in use. After four generations of development, e-cigarettes tend to be more customized and user-operable. The main components in the e-liquid and the aerosol are vegetable glycerin, propylene glycol, nicotine, organic acid and some flavor ingredients. Among them, nicotine is closely associated with the irritation and physiological satisfaction caused by tobacco products, and it is the core functional substance of e-cigarettes. For this reason, the quantification of nicotine content and nicotine form distribution mainly focuses on the components of the e-liquid and the released aerosol. Up to now, various technologies and methods have been applied in the analysis and research of nicotine content and nicotine form distribution in the e-liquid and its aerosol. GC-MS is often used as the most viable tool for the analysis of volatile organic compounds and can be widely applied in the measurement of nicotine related chemicals; there are a number of quantitation strategies using LC-MS, LC-MS/MS or 1H NMR for the analysis of e-cigarette samples. We also reviewed the four main methods for determining the distribution of nicotine forms, which are pH value derivation, solvent extraction, SPME and NMR methods. These research methods are of great significance to the upgrading and development of e-cigarette products.

Transformation between 2D covalent organic frameworks with distinct pore hierarchy via exchange of building blocks with different symmetries.

Transformation between 2D covalent organic frameworks (COFs) via exchange of molecular building blocks with different symmetries has been realized, which gives rise to the conversion between 2D COFs with distinct pore hierarchy. This type of monomer replacement has expanded the scope of the building-unit-exchange-based COF-to-COF transformation strategy.