1.
Chinese Journal of Endocrinology and Metabolism
; (12)2000.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-676724
RESUMO
The effect of 1-deoxynojirimycin(DNJ)on the proliferation of rat mesangial cells was observed and its mechanism was explored.The results showed that DNJ significantly inhibited the proliferation of rat mesangial cells induced by high glucose in time-and dose-dependent manners.DNJ significantly decreased expressions of?-smooth muscle action(?-SMA),integrin?1 mRNA and protein and focal adhesion kinase (FAK)protein stimulated by high glucose in rat mesangial cells(P