RESUMO
【Objective】 To retrospectively analyse the quality status and annual trend of centralized blood screening across the regions of Hubei province, and discuss the effect and advantages of the application of centralized blood screening across blood establishment. 【Methods】 Blood screening results of five blood establishment across Hubei province from 2005 to 2019 were statistically analyzed. The sample size, overall rate of qualified blood donations, overall and annual rate of positive testing items were compared among regions. 【Results】 There were differences in blood quality among different regions of Hubei province. In Wuhan, Ezhou, Xiantao, Tianmen and Qianjiang, the overall rate of qualified blood donations was 97.1%(2 466 396/2 538 871), 96.5%(85 405/88 547), 95.2%(59 087/62 047), 95.5%(68 920/72 146) and 94.7%(34 274/36 188), respectively; the overall deferral rate of ALT was 1.472% (37 374/2 538 871), 2.024% (1 792/88 547), 2.840% (1 762/62 047), 2.476% (1 786/72 146) and 3.777% (1 367/36 188), with significant differences across regions; the overall positive rate of HBsAg was 0.587% (14 897/2 538 871), 0.664% (588/88 547), 1.094% (679/62 047), 1.282% (925/72 146) and 0.862% (312/36 188), with significant differences across regions. The deferral rate of ALT showed a downward trend by year in these five regions from 2005 to 2019.An decreasing trend in the seroprevalence of HBV was noticed in Wuhan, Tianmen, and Qianjiang, HCV in Wuhan, Ezhou, and Tianmen, as well as syphilis infections in Wuhan. 【Conclusion】 Centralized blood screening can optimize the allocation of testing resources, reveal problems during blood collection and supply and improve the ability to guarantee blood safety. Future efforts are needed to expand the scope of centralized blood screening and seek for a centralized screening mode suitable for local situation.
