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1.
Pharmacol Res ; 204: 107203, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38719196

RESUMO

Recent research has demonstrated the immunomodulatory potential of Panax notoginseng in the treatment of chronic inflammatory diseases and cerebral hemorrhage, suggesting its significance in clinical practice. Nevertheless, the complex immune activity of various components has hindered a comprehensive understanding of the immune-regulating properties of Panax notoginseng, impeding its broader utilization. This review evaluates the effect of Panax notoginseng to various types of white blood cells, elucidates the underlying mechanisms, and compares the immunomodulatory effects of different Panax notoginseng active fractions, aiming to provide the theory basis for future immunomodulatory investigation.


Assuntos
Panax notoginseng , Panax notoginseng/química , Humanos , Animais , Sistema Imunitário/efeitos dos fármacos , Leucócitos/efeitos dos fármacos , Leucócitos/imunologia , Agentes de Imunomodulação/farmacologia , Agentes de Imunomodulação/uso terapêutico , Medicamentos de Ervas Chinesas/uso terapêutico , Medicamentos de Ervas Chinesas/farmacologia
2.
Environ Sci Pollut Res Int ; 31(11): 17052-17063, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38334929

RESUMO

Improving the adsorption performance of wetland fillers is of great significance for enhancing pollutant removal in constructed wetlands. Currently, limited by complex preparation processes and high costs, large numbers of high adsorption fillers studied in lab are difficult to be applied in practical engineering. In this study, a newly low-cost and efficient phosphorus removal composite wetland filler (CFB) is prepared by using industrial and agriculture waste (steel slag and oyster shells) and natural ore (volcanic rock) as raw materials. The results show that phosphorus removal efficiency was largely enhanced by synergistic effects of steel slag, oyster shells, and volcanic rock, and it was mainly influenced by the proportion of each component of CFB. Based on the fitting of the classical isothermal equation, the adsorption capacity of CFB is 18.339 mg/g. The adsorption of phosphorus by CFB is endothermic and spontaneous, and there are heterogeneous surfaces and multi-layer adsorption processes, as well as pH value and temperature, are free from the influence on CFB phosphorus removal. During the practical wastewater application experiments, the phosphorus removal rate of the CFB-filled constructed wetland apparatus (CW-A) can reach 94.89% and is free from the influence on the removal of other pollutants (COD, TN, and NH3-N) by the system. Overall, the prepared CFB is of excellent decontamination effect, an extremely simple preparation process, low cost, and sound practical engineering application potential, providing new ideas and approaches for enhancing the phosphorus removal capacity and waste resource utilization of constructed wetland systems.


Assuntos
Poluentes Ambientais , Eliminação de Resíduos Líquidos , Eliminação de Resíduos Líquidos/métodos , Áreas Alagadas , Fósforo , Águas Residuárias , Excipientes , Carbonato de Cálcio , Aço , Nitrogênio/análise
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