[Analysis of clinical features of mild chronic cadmium poisoning induced by different causes].

OBJECTIVE: To analyze the clinical features of mild chronic cadmium poisoning induced by different causes. METHODS: A total of 90 patients with mild chronic cadmium poisoning, who were hospitalized in our center from 2008 to 2011 and had complete clinical data, were divided into two groups according to the causes of poisoning: environmental pollution group (n = 45) and occupational poisoning group (n = 45). The clinical symptoms, signs, laboratory indices, and treatment outcomes of all patients were analyzed. RESULTS: Compared with the environmental pollution group, the occupational poisoning group had more bone pain, less bone injury (based on imaging findings), and significantly increased abnormal rate of urinary retinol-binding protein (RBP) (P < 0.05); there were no significant differences in urinary ß-2 microglobulin (MG) and urinary microalbumin between the two groups (P > 0.05). Urinary cadmium, urinary RBP, and urinary ß-2 MG had no linear correlation between each other in the two groups. Both groups showed significant changes in urinary cadmium levels after treatment (P < 0.05). CONCLUSION: The clinical features of mild chronic cadmium poisoning induced by various causes are different, and active nutritional support therapy plays a positive role in improving prognosis.

[Study on modified anesthesia in the bronchoalveolar lavage of pneumoconiosis].

OBJECTIVE: To observe the anesthetic effect of modified anesthesia in the bronchoalveolar lavage. METHOD: 118 cases randomly fell in two groups: traditional group: intramuscular injection of 10 mg diazepam prior to routine anesthesia; modified group: preoperative intramuscular injection of 50 mg dolantin,and venous injection of 2 ml physiological saline, 10 mg dexamethasone, 5 mg ephedrine; observe the anesthetic effect, satisfaction and lavage quantity in patients. RESULTS: The excellence rate and satisfaction of anesthetic effect are both 100% in modified group while 82.76% and 76.2% in the tradition group. The result indicates the excellence rate and satisfaction of anesthetic effect in modified group are better than the traditional group with a significant difference (P<0.05); the lavage quantity in the modified group is significantly higher than that in the traditional group with a significant difference (P<0.01 ). CONCLUSION: Dolantin, dexamethasone and ephedrine preoperatively used with a good anesthetic effect can improve the cooperation of patients in bronchoalveolar lavage with less pain and increased lavage quantity, thereby worthy of clinical application.

[Clinical analysis of pneumonoconiosis complicated with spontaneous pneumothorax].

OBJECTIVE: To study the clinical characteristics and treatment method of pneumonoconiosis with spontaneous pneumothorax. METHODS: The clinical data of 55 cases with spontaneous pneumothorax were analyzed. RESULTS: Among these 55 cases, there were 19 cases with left side pneumothorax, 25 cases with right side pneumothorax and 11 cases with bilateral pneumothorax. The lungs of 17 cases were compressed to less than 20%, the lungs of 29 cases were compressed to 20% ∼ 50% and the lungs of 9 cases were compressed to more than 50%, 17 cases were treated conservatively, 7 cases were treated by thoracentesis, and 32 cases were treated by closed thoracic drainage, including 10 cases intrapleural injected with thrombin and PAMBA. After the treatment, 41 cases were cured, 10 cases were improved, 3 cases were transferred to other hospital for plugging or pleurodesis and 1 case died of the respiratory failure. CONCLUSION: The clinical symptoms of cases with pneumonoconiosis and spontaneous pneumothorax are atypical. These cases easily recur. After treatment, the healing of these cases is better.