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Objective To analyze the effect of the new type of Enteral Nutritional Emulsion on the blood glucose and serum level of serum calcitonin in patients with acute respiratory failure.Methods 62 acute respiratory failure with stress hyperglycemia patients were selected and randomLy divided into observation group(n=31) and control group(n=31) in our hospital from April 2013 to August 2016, the control group was treated with Enteral Nutritional Suspension, the observation group was treated with New Enteral Nutritional Emulsion.We compared the two groups before treatment and after 10 days of fasting blood glucose(FBG), 2 hour postprandial blood glucose(2hPBG), serum procalcitonin(PCT) and interleukin-6(IL-6), C reactive protein(CRP) level, and statistics of the incidence of adverse reactions of the two groups.Results Comparing with the control group, the FBG and 2hPBG of the observation group was significantly lower than that of the control group after 10 days treatment, and the difference was statistically significant(P0.05).Conclusion The new type of Enteral Nutritional Emulsion in the treatment of acute respiratory failure with stress hyperglycemia can effectively control the blood glucose level and reduce the concentration of serum calcitonin.
RESUMO
Objective] To explore the effect of Biejiajian oral Liquid (BOL) on the level of angiotensinⅡ(AngⅡ) and angiotensin(1-7) [Ang(1-7)],and ratio of AngⅡ/Ang(1-7) in liver fibrosis rats. [Methods] Randomly divide male Wistar rats into blank group, model group, BOL groups of high dose and low dose, 10 in each. The model rats were injected with inactivated pig serum abdominally, 0.5mL for each, 2 times/w, for successive 8w. Other rats were injected with the same dosage and period of normal saline. After modeling, administer BOL 10g·kg-1 to low-dose groups rats, and 20g·kg-1 to high-dose group rats; give equal distilled water to blank and model groups, for successive 5 weeks of intragastric administration. The liver histopathology was examined by hematoxylin-eosin(HE) and Masson trichrome staining. Liver and spleen index were calculated. Levels of alanine transaminase(ALT) and aspartate aminotransferase(AST) in serum were assayed by automatic biochemistry detection instrument. Contents of hyaluronic acid(HA), laminin(LN), typeⅢprocollagen(PcⅢ) and type IV collagen(Ⅳ.C) in serum were detected by radioimmunoassay. AngⅡand Ang(1-7) levels were determined by enzyme linked immunosorbent assay. [Results] Compared with model group, the histological injury of liver in rats of BOL groups was relieved; serum levels of AST, ALT, HA, LN, PCⅢ and Ⅳ.C, and the content of AngⅡ in liver homogenate were decreased significantly than that of the model group. Ang(1-7) level was further increased, AngⅡ/Ang(1-7) ratio was decreased obviously in BOL groups. [Conclusion] BOL showed the protective function for hepatic fibrosis, the mechanisms of which may be associated with improvement of Ang(1-7) level, decrease of AngⅡlevel and the ratio of AngⅡand Ang(1-7).