RESUMO
AIM: To investigate the chemical constituents of Murraya kwangsiensis. METHODS: Compounds were isolated by silica gel column chromatography and TLC method, respectively. Structures of compounds were elucidated by spectral (UV, IR, MS, 1HNMR and 13CNMR) analysis. RESULTS: Five carbazole alkaloids and two other compounds were isolated and identified. Six of them are known compounds: murrayafoline A, murrayanine, koenine, isomahanine, palmitic acid and beta-sitosterol. One is a new alkaloid, named kwangsine. CONCLUSION: A new alkaloid, named kwangsine, was isolated from Murraya kwangsiensis Var. Six known compounds were isolated from this plant for the first time.
Assuntos
Alcaloides/química , Plantas Medicinais/química , Alcaloides/isolamento & purificaçãoRESUMO
Chrysanthemum indicum L. is a Chinese traditional drug used for antifebrile, detoxication and hypotensive purposes. In continuation of our efforts to search for the active principles of this species, a new sesquiterpene compound, named chrysanthetriol was isolated from the more polar fraction of the title plant. Chrysanthetriol is a colorless oil, [alpha]D20-31.8 degrees (c 0.3, MeOH). HRMS showed the molecular formula to be C15H26O3. The structure and stereochemistry of chrysanthtriol was elucidated as I by the use of 1H-1H COSY, 1H-13C COSY, 1H-13C COLOC 2D NMR spectroscopy.
Assuntos
Anti-Inflamatórios não Esteroides/química , Sesquiterpenos/química , Medicamentos de Ervas Chinesas/química , Espectroscopia de Ressonância Magnética/métodos , Conformação Molecular , Sesquiterpenos/isolamento & purificaçãoRESUMO
Three triterpene compounds have been isolated from the roots of Tripterygium wilfordii Hook F. The structure of the new compound, 3-hydroxy-25-norfriedel-3, 1 (10)-dien-2-one-30 oic acid named tripterygone (III), and the identity of others, 3 beta, 22 beta-dihydroxy-delta 12-oleanen-29-oic acid (I) and 2 alpha, 3 alpha, 24-trihydroxy-delta 12-ursene-28-oic acid (II) have been established by spectral data and physical properties. Compound II was isolated for the first time from the title plant.
Assuntos
Anti-Inflamatórios não Esteroides , Medicamentos de Ervas Chinesas/química , Triterpenos/isolamento & purificação , TripterygiumRESUMO
A new amide named podocarpamide (IX) was isolated from the bark of Zanthoxylum podocarpum Hemsl. By means of spectral analysis combined with chemical reactions, the structure has been elucidated.
