Cost-effectiveness and cost-utility of a digital technology-driven hierarchical healthcare screening pattern in China.

Utilization of digital technologies for cataract screening in primary care is a potential solution for addressing the dilemma between the growing aging population and unequally distributed resources. Here, we propose a digital technology-driven hierarchical screening (DH screening) pattern implemented in China to promote the equity and accessibility of healthcare. It consists of home-based mobile artificial intelligence (AI) screening, community-based AI diagnosis, and referral to hospitals. We utilize decision-analytic Markov models to evaluate the cost-effectiveness and cost-utility of different cataract screening strategies (no screening, telescreening, AI screening and DH screening). A simulated cohort of 100,000 individuals from age 50 is built through a total of 30 1-year Markov cycles. The primary outcomes are incremental cost-effectiveness ratio and incremental cost-utility ratio. The results show that DH screening dominates no screening, telescreening and AI screening in urban and rural China. Annual DH screening emerges as the most economically effective strategy with 341 (338 to 344) and 1326 (1312 to 1340) years of blindness avoided compared with telescreening, and 37 (35 to 39) and 140 (131 to 148) years compared with AI screening in urban and rural settings, respectively. The findings remain robust across all sensitivity analyses conducted. Here, we report that DH screening is cost-effective in urban and rural China, and the annual screening proves to be the most cost-effective option, providing an economic rationale for policymakers promoting public eye health in low- and middle-income countries.

Attitudes towards medical artificial intelligence talent cultivation: an online survey study.

BACKGROUND: To investigate the attitude and formal suggestions on talent cultivation in the field of medical artificial intelligence (AI). METHODS: An electronic questionnaire was sent to both medical-related field or non-medical field population using the WenJuanXing web-application via social media. The questionnaire was designed to collect: (I) demographic information; (II) perception of medical AI; (III) willingness to participate in the medical AI related teaching activities; (IV) teaching content of medical AI; (V) the role of medical AI teaching; (VI) future career planning. Respondents' anonymity was ensured. RESULTS: A total of 710 respondents provided valid answers to the questionnaire (57.75% medical related, 42.25% non-medical). About 73.8% of respondents acquired related information from network and social platform. More than half the respondents had basic perception of AI applicational scenarios and specialties in medicine, meanwhile were willing to participate in related general science activities (conference and lectures). Respondents from medical healthcare related fields, with high academic qualifications of male ones demonstrated showed significant better understanding and stronger willingness (P<0.05). The majority agreed medical AI courses should be set as major elective (42.82%) during undergraduate stages (89.58%) involving medical and computer science contents. An overwhelming majority of respondents (>80%) acknowledged the potential roles of medical AI teaching. Surgeon, ophthalmologist, physicians and researchers are the top tier considerations for ideal career regardless of AI influence. Radiology and clinical laboratory subjects are more preferred considering the development of medical AI (P>0.05). CONCLUSIONS: The potential role of medical AI talent cultivation is widely acknowledged by public. Medical related professions demonstrated higher level of perception and stronger willingness for medical AI educational events. Merging subjects as radiology and clinical laboratory subjects are preferred with broad talents demands and bright prospects.

Application of artificial intelligence in anterior segment ophthalmic diseases: diversity and standardization.

Artificial intelligence (AI) based on machine learning (ML) and deep learning (DL) techniques has gained tremendous global interest in this era. Recent studies have demonstrated the potential of AI systems to provide improved capability in various tasks, especially in image recognition field. As an image-centric subspecialty, ophthalmology has become one of the frontiers of AI research. Trained on optical coherence tomography, slit-lamp images and even ordinary eye images, AI can achieve robust performance in the detection of glaucoma, corneal arcus and cataracts. Moreover, AI models based on other forms of data also performed satisfactorily. Nevertheless, several challenges with AI application in ophthalmology have also arisen, including standardization of data sets, validation and applicability of AI models, and ethical issues. In this review, we provided a summary of the state-of-the-art AI application in anterior segment ophthalmic diseases, potential challenges in clinical implementation and our prospects.

Macroscopic supramolecular assembly of rigid hydrogels assisted by a flexible spacing coating.

To address the difficult challenge of realizing macroscopic supramolecular assembly (MSA) of high-modulus hydrogels, we propose a strategy of introducing a flexible spacing coating to improve the surface compliance for efficient MSA, which holds promise to develop versatile MSA methods for fabricating hydrogel-based tissue scaffolds, and to provide insight into the MSA mechanism.