1.
Org Lett
; 20(15): 4622-4626, 2018 08 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30004707
RESUMO
The first gold(III)-catalyzed regioselective oxidation/cycloisomerization of diynes 1 with pyridine N-oxide as the oxidant was developed, providing a range of synthetically valuable and useful fused furan derivatives 3 in moderate to good yields. Control experiments and the confirmation structure of minor products 5 suggest that this chemistry was a concerted gold(III)-catalyzed oxidation/SN2'-type addition/cyclization process via a ß-gold vinyloxypyridinium intermediate and a putative vinyl cation intermediate.