RESUMO
BACKGROUND: Esophageal perforation remains a devastating event that is difficult to diagnose and manage. The overall mortality associated with esophageal perforation can approach 20%, and delay in treatment of more than 24 hours after perforation can result in a doubling of mortality. The treatment option for esophageal perforation with mediastinitis is not very clear and still controversial. METHODS: Between April 2000 and March 2004, 6 males and 2 females, with ages ranging from 2 to 6 years (mean, 3.8 years), underwent videothoracoscopic drainage for esophageal perforation with mediastinitis. RESULTS: The mean hospital length of stay for patients in our series was 34.1 days (range, 14-47 days). There was no perioperative mortality. All patients were discharged from hospital without major sequelae. CONCLUSIONS: Minimally invasive videothoracoscopic drainage is a feasible and effective method for esophageal perforation with mediastinitis in children.
Assuntos
Perfuração Esofágica/cirurgia , Mediastinite/cirurgia , Criança , Pré-Escolar , Drenagem/métodos , Perfuração Esofágica/complicações , Perfuração Esofágica/etiologia , Feminino , Reação a Corpo Estranho , Humanos , Doença Iatrogênica , Tempo de Internação , Masculino , Mediastinite/etiologia , Cirurgia Torácica Vídeoassistida/métodos , Resultado do TratamentoRESUMO
Objective To realize the relationship between substance P(SP) and abnormal gastrointestinal tran- sit. Methods By radioimmunoassay, concentration of SP in sigmoid mucosa was determined in 12 healthy volun- teers, 15 slow and 10 fast transit patients. ResultsThe concentration was (27.68±15.42)μg/g, (24.07+5.76)μg/g and (28.61± 18.34)μg/g,respectively. They had no statistical difference. Conclusion There was no relationship be- tween concentration of SP in sigmoid mucosa and abnormal gastrointestinal transit.
