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1.
Sci Total Environ ; 768: 144865, 2021 May 10.
Artigo em Inglês | MEDLINE | ID: mdl-33434810

RESUMO

The North China Grid has the highest proportion of fossil fuel-based electricity generation in China and also suffers from severe water scarcity issues. This study uses a multi-objective optimization model to explore future configurations of generating and cooling technologies of the electric power sector in the North China Grid subject to constraints imposed by existing policies on water conservation and carbon reduction in 2030. Our findings highlight that the current carbon reduction commitments of China do not have significant impacts on the North China Grid's electric power sector development while policies in the water sector generate much larger impacts. Imposing water constraint according to the 'Three Red Line' Policy requires increasing utilization of wind power and air cooling systems, which simultaneously increases economic cost and carbon emissions compared to the business as usual scenario. Imposing enhanced carbon emission and water consumption constraints reap the co-benefits of carbon reduction and water conservation by increasing the proportion of solar PV generation to 8.21%, which increases the unit electricity cost from RMB 0.82 per kWh to RMB 1.37 per kWh. In 2030, electricity generation in the North China Grid generates 1599.88 to 1690.89 million tons (Mt) of carbon emissions under different scenarios whereas imposing water constraint reduces water consumption from 3.34 billion m3 to 1.94 billion m3.

2.
Sci Total Environ ; 756: 143853, 2021 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-33293095

RESUMO

Electric vehicles (EVs) are promoted in recent years as an effective way in alleviating the air pollution caused by tailpipe emissions. However, the pollutants derived from EVs are unheeded. EVs rely on electricity to provide power, and thus their related pollution is transferred to the power plants, which gives rise to the environmental and health pressure to the adjacent regions. In this paper, the transfer of EV-attributed PM2.5, SO2, and NOx inhalations in China are studied. Then by comparing the inhalations versus traffic accessibility among the impacted municipalities, this study sheds light on the environmental injustice lying in the mismatch between pollutant inhalations and traffic accessibility. The results reveal that compared with Shanghai and Shenzhen, the promotion of EVs in Beijing triggers higher pollutant inhalations to its surrounding municipalities. North China Power Grid undertakes 715.62 g PM2.5 inhalation in total, which is 2.51 and 3.20 times higher than the East China Power Grid and the China Southern Power Grid, respectively. The number of municipalities with lower traffic accessibility while higher pollutant inhalation is 8,8, and 17 in North China Power Grid, East China Power Grid, and China Southern Power Grid respectively, indicating conspicuous environmental injustice resulted from the promotion of EVs.

3.
Waste Manag ; 102: 579-586, 2020 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-31770692

RESUMO

The environmental threats posed by spent lithium-ion batteries (LIBs) and the future supply risks of battery components for electric vehicles can be simultaneously addressed by remanufacturing spent electric vehicle LIBs. To figure out the feasibility of battery remanufacturing, this paper quantifies the environmental impacts and costs of the remanufacturing of lithium-nickel-manganese-cobalt oxide battery cells and compares the results with the production of batteries from virgin materials. Based on the EverBatt model, a China-specific database of hydrometallurgical remanufacturing process is established. The results indicate that the reductions in energy consumption and greenhouse gas emissions by battery remanufacturing are 8.55% and 6.62%, respectively. From the economic standpoint, the potential cost-saving from battery remanufacturing is approximately $1.87 kg-1 cell produced. Through a sensitivity analysis, LIB remanufacturing is found to be economically viable until the purchase price of spent batteries rises to $2.87 kg-1. Furthermore, the impact of battery type variability is prominent, whereas the influence of recovery efficiency is limited.


Assuntos
Fontes de Energia Elétrica , Lítio , China , Análise Custo-Benefício , Eletricidade
4.
J Ethnopharmacol ; 141(1): 41-7, 2012 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-22370553

RESUMO

AIM OF THE STUDY: This study was aimed to evaluate the neuroprotective and anti-aging activity of extracts in Caenorhabditis elegans from the roots and leaves of Damnacanthus officinarum Huang to provide the pharmacological basis in traditional medicine. MATERIALS AND METHODS: Investigations on the neuroprotective and lifespan activity were carried out, which were observed by utilizing the following models: observing the worms' chemosensory behavior test based on the aversion index in the assay plate, neuroprotective activity of nematode by evaluating the ASH neuron survival and lifespan test in C. elegans. RESULTS: It has been shown that the ethanol, n-butanol and aqueous extracts in the roots possessed significantly neuroprotective effect both in chemosensory behavior test and ASH neuron survival model. The same extracts in the leaves showed similar activities in two models, but have less potency revealing by the data. Four candidate extracts, possessing excellent neuroprotective activity, extend lifespan in C. elegans. The n-butanol extracts in the root part showed best efficacy among them. CONCLUSION: The results show the n-butanol and aqueous extracts are the major pharmacological plant extracts. Moreover, the neuroprotective and lifespan-extension activity effects of root extracts are superior to leave extracts, supporting the traditional application of above-ground parts of DOH in treating various diseases associated with brain disorders and anti-aging.


Assuntos
Caenorhabditis elegans/efeitos dos fármacos , Longevidade/efeitos dos fármacos , Neurônios/efeitos dos fármacos , Fármacos Neuroprotetores/farmacologia , Extratos Vegetais/farmacologia , Rubiaceae , 1-Butanol/química , Animais , Animais Geneticamente Modificados , Caenorhabditis elegans/genética , Caenorhabditis elegans/metabolismo , Sobrevivência Celular/efeitos dos fármacos , Células Quimiorreceptoras/efeitos dos fármacos , Células Quimiorreceptoras/metabolismo , Relação Dose-Resposta a Droga , Etanol/química , Neurônios/metabolismo , Neurônios/patologia , Fármacos Neuroprotetores/química , Fármacos Neuroprotetores/isolamento & purificação , Fitoterapia , Extratos Vegetais/química , Extratos Vegetais/isolamento & purificação , Folhas de Planta , Raízes de Plantas , Plantas Medicinais , Rubiaceae/química , Solventes/química , Fatores de Tempo
5.
Biochem J ; 441(1): 417-24, 2012 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-21892924

RESUMO

Late-onset neurodegenerative diseases are characterized by progressive accumulation of aggregation-prone proteins and global disruption of the proteostasis network, e.g. abnormal polyQ (polyglutamine) aggregation in Huntington's disease. Astragalus membranaceus polysaccharide (astragalan) has recently been shown to modulate aging and proteotoxic stress pathways. Using Caenorhabditis elegans models, we now show that astragalan not only reduces polyQ aggregation, but also alleviates the associated neurotoxicity. We also reveal that astragalan can extend the adult lifespan of wild-type and polyQ nematodes, indicating a connection of its anti-aging benefit with the toxicity-suppressing effect. Further examination demonstrates that astragalan can extend the lifespan of daf-2 and age-1, but not daf-16, mutant nematodes of the insulin-like aging and stress pathway, suggesting a lifespan-regulation signalling independent of DAF (abnormal dauer formation)-2/IGF-1R (insulin-like growth factor 1 receptor), but dependent on the DAF-16/FOXO (forkhead box O) transcription factor, a pivotal integrator of divergent signalling pathways related to both lifespan regulation and stress resistance. We also show that a subset of DAF-16 downstream genes are regulated by astragalan, including the DAF-16 transcriptional target gene scl-20, which is itself constitutively up-regulated in transgenic polyQ nematodes. These findings, together with our previous work on LEA (late embryogenesis abundant) proteins and trehalose, provide a revealing insight into the potential of stress and lifespan regulators in the prevention of proteotoxic disorders.


Assuntos
Astragalus propinquus/química , Proteínas de Caenorhabditis elegans/metabolismo , Fatores de Transcrição Forkhead/metabolismo , Peptídeos/metabolismo , Polissacarídeos/farmacologia , Fatores de Transcrição/metabolismo , Animais , Proteínas de Caenorhabditis elegans/genética , Sobrevivência Celular , Retículo Endoplasmático , Fatores de Transcrição Forkhead/genética , Regulação da Expressão Gênica/efeitos dos fármacos , Neurônios/efeitos dos fármacos , Estresse Oxidativo/efeitos dos fármacos , Polissacarídeos/química , Fatores de Transcrição/genética
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