Case report: Paraneoplastic lower motor neuronopathy associated with a malignant liver tumor.

Paraneoplastic lower motor neuronopathies (LMNs) have rarely been reported with malignant liver tumors. A 71-year-old man developed chronic progressive upper limb and cranial nerve paralysis. Electromyography examination suggests chronic progressive neuronal damage involving the right C4-T1 nerve root innervated muscle and the right sternocleidomastoid muscle. Magnetic resonance imaging suggested the presence of a malignant liver tumor. His serum was positive for anti-Yo antibodies. Hepatic artery chemoembolization was performed, followed by treatment with pembrolizumab and lenvatinib. The patient's condition improved, and paraneoplastic LMNs were diagnosed. Paraneoplastic causes should be considered in the differential diagnosis of chronic progressive LMNs. A combination of surgical treatment and immunotherapy may result in a favorable outcome.

Assessing the development potential of non-food biofuel crops under the water-land-biofuel nexus perspective.

Facing water and land scarcity, planting non-food biofuel crops on marginal land depending on natural rainfall has been considered as an attractive means of achieving sustainable biofuel development. However, the complex connection between rainfall and marginal land resources in spatial-temporal distribution affects the optimal planting layout of non-food biofuel crops as well as the assessment of biofuel potential, especially in arid areas. In this study, we constructed a water-land-biofuel nexus centered on non-food biofuel crops, optimized the layout of three non-food biofuel crops, sweet sorghum, Jerusalem artichoke and switchgrass, based on fuzzy mathematics method under the water-land-biofuel nexus perspective, determined yield-rainfall curve to calculate the development potential of non-food biofuel crops. The results showed that sweet sorghum and Jerusalem artichoke are more suitable for planting in Ningxia. Three potential scenarios are set up under different growth conditions and agricultural technologies. The theoretical biofuel production is [9.64× 107, 10.93× 107] GJ, which was verified by the result that the biofuel production per unit area is close to the lower limit of the test production range. It can also be speculated that there may exist irrigation supply and fertilization in the actual crops planting in other studies.

Effect of Double-Channel Anastomosis and Esophagojejunal Anastomosis on Postoperative Recovery and Complications of Laparoscopic D2 Radical Gastrectomy for Gastric Cancer.

The aim of this study was to investigate the effects of double-channel anastomosis versus esophagojejunostomy on postoperative recovery and complications after laparoscopic D2 radical gastrectomy for early proximal gastric cancer. The cases were collected from 100 patients with early proximal gastric cancer admitted to our hospital from January 2017 to January 2021. According to different surgical methods, they were divided into control group (total gastrectomy + esophagojejunal anastomosis) and experimental group (D2 radical resection + double-channel anastomosis). The two groups were compared in terms of clinical outcomes (operative time, intraoperative blood loss, number of lymph nodes dissected, digestive tract anastomosis time, postoperative exhaust, and hospitalization days), postoperative complications, and nutritional status; the expression of T lymphocyte subsets in peripheral blood of the two groups was detected to reflect the recovery of immune ability. There was no significant difference between the observation group and the control group in clinical operation effect indexes (P < 0.05). The incidence of complications of dumping syndrome and reflux esophagitis in the observation group was significantly lower than that in the control group (P < 0.05). In terms of postoperative nutritional status, the ratio of plasma albumin level and body weight restored to operation at 12 and 24 weeks after operation in the observation group was significantly higher than that in the control group (P < 0.05). 3 months after the operation, the levels of CD3 +, CD4 + cell subsets, and CD4+/CD8+ index reflecting the recovery of immune ability in the observation group were significantly higher than those in the observation group (P < 0.05). The application of double-channel anastomosis in laparoscopic D2 radical gastrectomy for early proximal gastric cancer has a better effect on reducing complications and promoting postoperative recovery, which is of great application value.

An Interface Heterostructure of NiO and CeO2 for Using Electrolytes of Low-Temperature Solid Oxide Fuel Cells.

Interface engineering can be used to tune the properties of heterostructure materials at an atomic level, yielding exceptional final physical properties. In this work, we synthesized a heterostructure of a p-type semiconductor (NiO) and an n-type semiconductor (CeO2) for solid oxide fuel cell electrolytes. The CeO2-NiO heterostructure exhibited high ionic conductivity of 0.2 S cm-1 at 530 °C, which was further improved to 0.29 S cm-1 by the introduction of Na+ ions. When it was applied in the fuel cell, an excellent power density of 571 mW cm-1 was obtained, indicating that the CeO2-NiO heterostructure can provide favorable electrolyte functionality. The prepared CeO2-NiO heterostructures possessed both proton and oxygen ionic conductivities, with oxygen ionic conductivity dominating the fuel cell reaction. Further investigations in terms of electrical conductivity and electrode polarization, a proton and oxygen ionic co-conducting mechanism, and a mechanism for blocking electron transport showed that the reconstruction of the energy band at the interfaces was responsible for the enhanced ionic conductivity and cell power output. This work presents a new methodology and scientific understanding of semiconductor-based heterostructures for advanced ceramic fuel cells.

Simulate Deutsch-Jozsa algorithm with metamaterials.

During the past few years, a lot of efforts have been devoted in studying optical analog computing with artificial structures. Up to now, much of them are primarily focused on classical mathematical operations. How to use artificial structures to simulate quantum algorithm is still to be explored. In this work, an all-dielectric metamaterial-based model is proposed and realized to demonstrate the quantum Deutsch-Jozsa algorithm. The model is comprised of two cascaded functional metamaterial subblocks. The oracle subblock encodes the detecting functions (constant or balanced), onto the phase distribution of the incident wave. Then, the original Hadamard transformation is performed with a graded-index subblock. Both the numerical and experimental results indicate that the proposed metamaterials are able to simulate the Deutsch-Jozsa problem with one round operation and a single measurement of the output eletric field, where the zero (maximum) intensity at the central position results from the destructive (constructive) interference accompanying with the balance (constant) function marked by the oracle subblock. The proposed computational metamaterial is miniaturized and easy-integration for potential applications in communication, wave-based analog computing, and signal processing systems.