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1.
Micromachines (Basel) ; 14(4)2023 Apr 19.
Artigo em Inglês | MEDLINE | ID: mdl-37421114

RESUMO

Fiber-reinforced composites (FRC) are widely used in various fields due to their excellent mechanical properties. The mechanical properties of FRC are significantly governed by the orientation of fibers in the composite. Automated visual inspection is the most promising method in measuring fiber orientation, which utilizes image processing algorithms to analyze the texture images of FRC. The deep Hough Transform (DHT) is a powerful image processing method for automated visual inspection, as the "line-like" structures of the fiber texture in FRC can be efficiently detected. However, the DHT still suffers from sensitivity to background anomalies and longline segments anomalies, which leads to degraded performance of fiber orientation measurement. To reduce the sensitivity to background anomalies and longline segments anomalies, we introduce the deep Hough normalization. It normalizes the accumulated votes in the deep Hough space by the length of the corresponding line segment, making it easier for DHT to detect short, true "line-like" structures. To reduce the sensitivity to background anomalies, we design an attention-based deep Hough network (DHN) that integrates attention network and Hough network. The network effectively eliminates background anomalies, identifies important fiber regions, and detects their orientations in FRC images. To better investigate the fiber orientation measurement methods of FRC in real-world scenarios with various types of anomalies, three datasets have been established and our proposed method has been evaluated extensively on them. The experimental results and analysis prove that the proposed methods achieve the competitive performance against the state-of-the-art in F-measure, Mean Absolute Error (MAE), Root Mean Squared Error (RMSE).

3.
Genomics Insights ; 9: 1-16, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27006591

RESUMO

Ganoderma lucidum (lingzhi) has been used for the general promotion of health in Asia for many centuries. The common method of consumption is to boil lingzhi in water and then drink the liquid. In this study, we examined the potential anticancer activities of G. lucidum submerged in two commonly consumed forms of alcohol in East Asia: malt whiskey and rice wine. The anticancer effect of G. lucidum, using whiskey and rice wine-based extraction methods, has not been previously reported. The growth inhibition of G. lucidum whiskey and rice wine extracts on the prostate cancer cell lines, PC3 and DU145, was determined. Using Affymetrix gene expression assays, several biologically active pathways associated with the anticancer activities of G. lucidum extracts were identified. Using gene expression analysis (real-time polymerase chain reaction [RT-PCR]) and protein analysis (Western blotting), we confirmed the expression of key genes and their associated proteins that were initially identified with Affymetrix gene expression analysis.

4.
Phytochemistry ; 114: 56-65, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25794896

RESUMO

Medicinal mushrooms have been used for centuries as nutraceuticals to improve health and to treat numerous chronic and infectious diseases. One such mushroom is Ganoderma lucidum, commonly known as Lingzhi, a species revered as a medicinal mushroom for treating assorted diseases and prolonging life. The fungus is found in diverse locations, and this may have contributed to confusion regarding the correct taxonomic classification of the genus Ganoderma. G. lucidum was first used to name a specimen found in England and thereafter was naively applied to a different Ganoderma species found in Asia, commonly known as Chinese Lingzhi. Despite the taxonomic confusion, which has largely been uncorrected, the popularity of Lingzhi has escalated across the globe. The current taxonomic situation is now discussed accurately in this Special Issue on Ganoderma. Today it is a multi-billion dollar industry wherein Lingzhi is cultivated or collected from the wild and consumed as a tea, in alcoholic beverages, and as a nutraceutical to confer numerous health benefits. Consumption of nutraceuticals has grown in popularity, and it is becoming increasingly important that active ingredients be identified and that suppliers make substantiated health claims about their products. The objective of this article is to present a review of G. lucidum over the past 2000 years from prized ancient "herbal" remedy to its use in nutraceuticals and to the establishment of a 2.5 billion $ (US) industry.


Assuntos
Antivirais/farmacologia , Reishi/química , Triterpenos/farmacologia , Antivirais/química , Antivirais/isolamento & purificação , Bases de Dados Factuais , Inglaterra , Estrutura Molecular , Triterpenos/química , Triterpenos/isolamento & purificação
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