1.
Org Biomol Chem
; 22(23): 4651-4655, 2024 06 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38787760
RESUMO
An arylazopyrazole-based covalent inhibitor targeting the mitotic motor protein of centromere-associated protein E (CENP-E) was developed. Using this photoswitchable inhibitor, a photoswitchable CENP-E was chemically constructed in cells, which enabled to local control of mitotic cell division with light illumination.