Calidad de vida de los pacientes tratados con anticoagulantes orales / Quality of life of patients treated with oral anti-coagulants

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[Cross-cultural adaptation of a questionnaire for measuring the quality of life of patients taking oral anticoagulants]. / Adaptación transcultural de un cuestionario para medir la calidad de vida de los pacientes con anticoagulación oral.

OBJECTIVE: To adapt to Spanish culture and language a questionnaire developed to evaluate the quality of life of patients taking oral anticoagulation treatment (OAT) and to measure its validity. DESIGN: A descriptive observation study to validate an instrument to measure health-related quality of life. SETTING: Primary and specialist care. PARTICIPANTS: 225 patients, all the patients at our centre who were on OAT and a consecutive sample of patients on OAT from the referral hospital's haemotology service. MAIN MEASUREMENTS: Direct translation, back-translation, and pilot study. Factor analysis and item-dimension grouping, internal consistency analysis and analysis of the item-total correlation of the definitive version of the questionnaire in Spanish. RESULTS: Mean age was 65 (SD=13 years); 51% were women; 45.8% were monitored in PC. Validity study: factor analysis extracted 5 factors that explained 41.62% of total variance value and obtained a grouping different from the original; Cronbach's alpha was .82 overall and ran from .56 to .74 in the various dimensions; and item-total correlation analysis had statistically significant values, except for question 29. CONCLUSIONS: After adaptation to Spanish culture and language of a questionnaire developed to evaluate the quality of life of patients taking OAT, it was found to be a useful instrument, valid for use in our milieu.

Sonambulismo asociado con zolpidem / Sleep-walking lñinked to zolpidem

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