Observation of Non-Hermitian Edge Burst Effect in One-Dimensional Photonic Quantum Walk.

Non-Hermitian systems can exhibit unique quantum phases without any Hermitian counterparts. For example, the latest theoretical studies predict a new surprising phenomenon that bulk bands can localize and dissipate prominently at the system boundary, which is dubbed the non-Hermitian edge burst effect. Here we realize a one-dimensional non-Hermitian Su-Schrieffer-Heeger lattice with bulk translation symmetry implemented with a photonic quantum walk. Employing time-resolved single-photon detection to characterize the chiral motion and boundary localization of bulk bands, we determine experimentally that the dynamics underlying the non-Hermitian edge burst effect is due to the interplay of non-Hermitian skin effect and imaginary band gap closing. This new non-Hermitian physical effect deepens our understanding of quantum dynamics in open quantum systems.

Device-independent quantum randomness-enhanced zero-knowledge proof.

Zero-knowledge proof (ZKP) is a fundamental cryptographic primitive that allows a prover to convince a verifier of the validity of a statement without leaking any further information. As an efficient variant of ZKP, noninteractive zero-knowledge proof (NIZKP) adopting the Fiat-Shamir heuristic is essential to a wide spectrum of applications, such as federated learning, blockchain, and social networks. However, the heuristic is typically built upon the random oracle model that makes ideal assumptions about hash functions, which does not hold in reality and thus undermines the security of the protocol. Here, we present a quantum solution to the problem. Instead of resorting to a random oracle model, we implement a quantum randomness service. This service generates random numbers certified by the loophole-free Bell test and delivers them with postquantum cryptography (PQC) authentication. By employing this service, we conceive and implement NIZKP of the three-coloring problem. By bridging together three prominent research themes, quantum nonlocality, PQC, and ZKP, we anticipate this work to inspire more innovative applications that combine quantum information science and the cryptography field.

Experimental demonstration of free-space two-photon interference.

Quantum interference plays an essential role in understanding the concepts of quantum physics. Moreover, the interference of photons is indispensable for large-scale quantum information processing. With the development of quantum networks, interference of photons transmitted through long-distance fiber channels has been widely implemented. However, quantum interference of photons using free-space channels is still scarce, mainly due to atmospheric turbulence. Here, we report an experimental demonstration of Hong-Ou-Mandel interference with photons transmitted by free-space channels. Two typical photon sources, i.e., correlated photon pairs generated in spontaneous parametric down conversion (SPDC) process and weak coherent states, are employed. A visibility of 0.744 ± 0.013 is observed by interfering with two photons generated in the SPDC process, exceeding the classical limit of 0.5. Our results demonstrate that the quantum property of photons remains even after transmission through unstable free-space channels, indicating the feasibility and potential application of free-space-based quantum interference in quantum information processing.

Mortality analysis of captive red panda cubs within Chengdu, China.

BACKGROUND: The red panda has been classified as an endangered species due to the decreased number in the world and disease is considered as a great threat to the health and survival of the cubs in captivity. RESULTS: This study analyzed 32 red panda cub mortalities (15 females and 17 males, age less than two months) through gross necropsy, microbiological examination, and histopathological observation at the Chengdu Research Base of Giant Panda Breeding, China, during 2014-2020. The results showed that screenings for canine distemper virus, canine parvovirus, rotavirus and parasite infection were all negative, however bacteria such as Klebsiella pneumoniae, Proteus mirabilis, Escherichia coli, Enterococcus faecalis, Pseudomonas were isolated from the tissue samples of some cubs. The major causes of death were respiratory (43.75%) and digestive system disease (28.13%), followed by cardiovascular disease (12.5%) and neonatal stillbirths (9.38%). Renal system diseases and trauma were also detected, at lower incidence (one case for each). The mortality rate within 15 days of birth was 68.75% and gradually decreased with age, there was no significant difference in gender. CONCLUSION: This study can provide a scientific basis for the analysis of the cause of death among red panda cubs in captivity, so as to improve the survival rate, help build the captive population and further the ex-situ conservation management of this endangered species. Additionally, our research may also provide insights into the in-situ conservation of wild red pandas by identifying emerging disease threats within the wild population and potential treatment for rescued individuals.

Single-mode fiber coupling with a M-SPGD algorithm for long-range quantum communications.

Satellite-based quantum communication is a promising approach for realizing global-scale quantum networks. For free-space quantum channel, single-mode fiber coupling is particularly important for improving the signal-to-noise ratio of daylight quantum key distribution (QKD) and compatibility with standard fiber-based QKD. However, achieving a highly efficient and stable single-mode coupling efficiency under strong atmospheric turbulence remains experimentally challenging. Here, we develop a single-mode receiver with an adaptive optics (AO) system based on a modal version of the stochastic parallel gradient descent (M-SPGD) algorithm and test its performance over an 8 km urban terrestrial free-space channel. Under strong atmospheric turbulence, the M-SPGD AO system obtains an improvement of about 3.7 dB in the single-mode fiber coupling efficiency and a significant suppression of fluctuation, which can find its applications in free-space long-range quantum communications.

Isolation and characterization of Uropathogenic Escherichia coli (UPEC) from red panda (Ailurus fulgens).

BACKGROUND: Disease prevention and control is a significant part in the ex-situ conservation of the endangered red panda (Ailurus fulgens), being bacterial infection is one of the most important health threats to the captive population. To date, studies about the infection caused by Escherichia coli in the red panda are scarce. This study was conducted to determine the cause of death of a captive red panda through clinical symptoms, complete blood count, biochemical analysis, pathological diagnosis and bacterial whole genome sequencing. CASE PRESENTATION: The following report describes a case of a 1.5 year old captive red panda (Ailurus fulgens) that was found lethargic and anorectic. She was moved to the quarantine area for daily treatment with 50 mg of Cefpodoxime Proxetil. During the three-day treatment, she did not eat or defecate, and then died. Clinical hematology revealed the values of neutrophils, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and blood urea nitrogen (BUN) were significantly higher. Histological analysis demonstrated major pathological damage in the kidneys, liver and lungs, characterized by hyperemia, parenchymal cell degeneration and necrosis and inflammatory cell infiltration which were predominantly neutrophilic. A bacterial strain confirmed as Escherichia coli was isolated post mortem. Whole genome sequencing of the E. coli showed the complete genome size was 4.99 Mbp. PapA, PapC, OmpA, OmpU and other virulence factors which specific to Uropathogenic Escherichia coli (UPEC) were found in the isolate. Among the virulence factors, P pili, type I pili and related factors of the iron uptake system were associated with nephrotoxicity. CONCLUSION: The red panda died of bacterial infection caused by an uropathogenic strain of Escherichia coli. The pathogenic mechanisms of the strain are closely related to the expression of specific virulence genes.

Polarization design for ground-to-satellite quantum entanglement distribution.

High-fidelity transmission of polarization encoded qubits plays a key role in long distance quantum communication. By establishing the channel between ground and satellite, the communication distance can even exceed thousands of kilometers. Aimed to achieve the efficient uplink quantum communication, here we describe a high-fidelity polarization design of a transmitting antenna with an average polarization extinction ratio of 887:1 by a local test. We also implement a feasible polarization-compensation scheme for satellite motions with a fidelity exceeding 0.995 ± 0.001. Based on these works, we demonstrate the ground-to-satellite entanglment distribution with a violation of Bell inequality by 2.312±0.096, which is well above the classic limit 2.

Long-Distance Free-Space Measurement-Device-Independent Quantum Key Distribution.

Measurement-device-independent quantum key distribution (MDI-QKD), based on two-photon interference, is immune to all attacks against the detection system and allows a QKD network with untrusted relays. Since the MDI-QKD protocol was proposed, fiber-based implementations aimed at longer distance, higher key rates, and network verification have been rapidly developed. However, owing to the effect of atmospheric turbulence, MDI-QKD over a free-space channel remains experimentally challenging. Herein, by developing a robust adaptive optics system, high-precision time synchronization and frequency locking between independent photon sources located far apart, we realized the first free-space MDI-QKD over a 19.2-km urban atmospheric channel, which well exceeds the effective atmospheric thickness. Our experiment takes the first step toward satellite-based MDI-QKD. Moreover, the technology developed herein opens the way to quantum experiments in free space involving long-distance interference of independent single photons.

Point-ahead demonstration of a transmitting antenna for satellite quantum communication.

A low-divergence beam is an essential prerequisite for a high-efficiency long-distance optical link, particularly for satellite-based quantum communication. A point-ahead angle, caused by satellite motion, is always several times larger than the divergence angle of the signal beam. We design a novel transmitting antenna with a point-ahead function, and provide an easy-to-perform calibration method with an accuracy better than 0.2 µrad. Subsequently, our antenna establishes an uplink to the quantum satellite, Micius, with a link loss of 41-52 dB over a distance of 500-1,400 km. The results clearly confirm the validity of our model, and provide the ability to conduct quantum communications. Our approach can be adopted in various free space optical communication systems between moving platforms.

Free-space quantum key distribution in urban daylight with the SPGD algorithm control of a deformable mirror.

Free-space quantum key distribution (QKD) is important to realize a global-scale quantum communication network. However, performing QKD in daylight against the strong background light noise is a major challenge. Here, we develop the stochastic parallel gradient descent (SPGD) algorithm with a deformable mirror to improve the signal-to-noise ratio (SNR). We then experimentally demonstrate free-space QKD in the presence of urban daylight. The final secure key rate of the QKD is 98∼419 bps throughout the majority of the daylight hours.

Ground-to-satellite quantum teleportation.

An arbitrary unknown quantum state cannot be measured precisely or replicated perfectly. However, quantum teleportation enables unknown quantum states to be transferred reliably from one object to another over long distances, without physical travelling of the object itself. Long-distance teleportation is a fundamental element of protocols such as large-scale quantum networks and distributed quantum computation. But the distances over which transmission was achieved in previous teleportation experiments, which used optical fibres and terrestrial free-space channels, were limited to about 100 kilometres, owing to the photon loss of these channels. To realize a global-scale 'quantum internet' the range of quantum teleportation needs to be greatly extended. A promising way of doing so involves using satellite platforms and space-based links, which can connect two remote points on Earth with greatly reduced channel loss because most of the propagation path of the photons is in empty space. Here we report quantum teleportation of independent single-photon qubits from a ground observatory to a low-Earth-orbit satellite, through an uplink channel, over distances of up to 1,400 kilometres. To optimize the efficiency of the link and to counter the atmospheric turbulence in the uplink, we use a compact ultra-bright source of entangled photons, a narrow beam divergence and high-bandwidth and high-accuracy acquiring, pointing and tracking. We demonstrate successful quantum teleportation of six input states in mutually unbiased bases with an average fidelity of 0.80 ± 0.01, well above the optimal state-estimation fidelity on a single copy of a qubit (the classical limit). Our demonstration of a ground-to-satellite uplink for reliable and ultra-long-distance quantum teleportation is an essential step towards a global-scale quantum internet.

How the Canine Distemper Virus Infects Human Cells at the Molecular Level in Vitro.

Infection by the canine distemper virus (CDV) results in a fulminating infectious disease that causes serious harm to dogs. With breaking 'of the CDV into primates, some researchers wonder if the CDV will cause a serious infection in humans. To better understand the potential of the CDV to infect humans, the molecular characteristics of the CDV, how it infects target cells in the host, the key receptors involved in infection, and infection of human cells in vitro were assessed in this review. There is no direct evidence that CDV can colonize and grow in humans. Two key receptors, SLAM and nectin-4, in hunans and primates have high identity, and the CDV can infect human cells in vitro. Therefore, we must pay close attention to the potential threat of infection by the CDV in humans.

Effects of dissolved organic matter on phototransformation rates and dioxin products of triclosan and 2'-HO-BDE-28 in estuarine water.

Photochemical transformation of hydroxylated polyhalodiphenyl ethers (HO-PXDEs) has attracted much attention for their ubiquitous presence and the photochemical formation of highly toxic dioxins. Dissolved organic matter (DOM) plays an important role in the environmental photochemical transformation of organic pollutants. However, the effects of DOM on the photolysis kinetics and dioxin formation of HO-PXDEs are still not fully understood. Herein, the effects of Suwannee River natural organic matter (SRNOM) on the phototransformation of 2'-HO-2,4,4'-trichlorodiphenyl ether (triclosan) and 2'-HO-2,4,4'-tribromodiphenyl ether (2'-HO-BDE-28) were investigated in artificial estuarine water (AEW). The results showed that although SRNOM induced indirect photolysis of triclosan and 2'-HO-BDE-28, it decreased the observed photolytic rate constants due to light screening, static quenching and dynamic quenching effects. The above effects were quantified firstly. Direct photolysis is more important than indirect photolysis in the transformation of the target compounds and the production of dioxins. SRNOM increased the dioxin yields of the two HO-PXDEs. It was also found that SRNOM decreased the formation rate constant (kp) of 2,8-dichlorodibenzo-p-dioxin (2,8-DCDD) from triclosan and showed no obvious influence on the kp of 2,8-dibromodibenzo-p-dioxin (2,8-DBDD) from 2'-HO-BDE-28. SRNOM showed no obvious influence on the degradation of 2,8-DCDD, while it increased the degradation rate constant of 2,8-DBDD. The promoting effect on the degradation of 2,8-DBDD was attributed to the formation of chloride radicals with the concurrence of SRNOM and Cl(-) in AEW. This study revealed the roles of SRNOM in the photochemical transformation of HO-PXDEs and the photochemical formation and degradation of dioxins, which is important for elucidating the transformation fate of HO-PXDEs in aquatic environments.

[Canine Parvovirusin Diarrheal Dogs and Analyses of the Full-Length VP2 Gene of Dogs].

We investigated infection by canine parvovirus and genetic variation of the VP2 gene. We collected feces samples of 50 diarrheal dogs in Sichuan Province, China. Analyses polymerase chain reaction (PCRs), agarose gel electrophoresis, and amplification of the complete sequence of canine parvovirus were done. We observed 19PCR-positive samples. Sequencing analyses of 15PCR-positive samples based on amplification of the complete VP2 gene showed all to be CPV-2a,and to be polymerized with Sichuan isolates. These results suggest that the common epidemic strain in Sichuan Province is CPV-2a,and may originate from the same strain. Compared with reference strains, there were no significant variations in canine parvovirus in Sichuan Province, China.