1.
Org Lett
; 23(21): 8183-8188, 2021 Nov 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34664959
RESUMO
A nickel-catalyzed reductive cross coupling with phosphonium salts and allylic C(sp3)-O bond electrophiles, which granted direct construction of the C(sp2)-C(sp3) bond, is successfully developed. The protocol features broad substrate scope, high-functional-group tolerance, and heterocycle compatibility. Notably, the much more challenging reductive cross coupling with heterocyclic thiazolylphosphonium salts has also been accomplished for the first time.