RESUMO
Objective:To evaluate the subjective olfactory function in chronic sinusitisï¼CRSï¼patients with asthma after nasal endoscopic surgery and associated factors that may affect olfactory function. Methodsï¼The study included 90 CRS patients with asthma from January 2008 to December 2020ï¼and all of them underwent endoscopic sinus surgeryï¼ESSï¼. VAS score of olfactory function before and after surgery were collectedï¼and the data at baselineï¼3 monthsï¼6 monthsï¼1 yearï¼3 yearsï¼5 yearsï¼8 years and 10 years after surgery were compared. Factors affecting olfactory function were analyzed in a generalized mixed linear modelï¼which including ageï¼surgical procedureï¼allergic rhinitis and so on.Resultsï¼ The olfactory VAS scores were significantly lower at 3 monthsï¼6 monthsï¼1 yearï¼3 yearsï¼and 5 years postoperatively compared with baselineï¼and the difference was statistically significantï¼P<0.05ï¼.Olfactory VAS scores at 8 and 10 years postoperatively were not statistically different from baselineï¼P>0.05ï¼.Ageï¼≥60 yearsï¼ï¼aspirin intolerance syndromeï¼Lund-Kennedy scoreï¼modified sinus CT olfactory cleft scoreï¼and follow-up time were risk factors, and radical sinus surgery is a protective factor.Conclusionï¼Subjective olfactory scores in CRS patients with asthma after ESS remain relatively stable for 5 years postoperatively.Prior history of surgery did not affect postoperative subjective olfactory scores. Ageï¼aspirin intolerance syndrome, Lund-Kennedy scoreï¼modified sinus CT olfactory cleft score, follow-up timeï¼and surgical approach were strongly associated with subjective olfactory scores in CRS patients with asthmaï¼and radical surgery had a protective effect on olfaction.