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1.
Artigo em Inglês | MEDLINE | ID: mdl-38597296

RESUMO

Flexible pressure sensors (FPSs) based on biomass materials have gained considerable attention for their potential in wearable electronics, human-machine interaction, and environmental protection. Herein, flexible silver nanowire-dual-cellulose paper (SNdCP) containing common cellulose fibers, cellulose nanofibers (CNFs), and silver nanowires (AgNWs) for FPSs was assembled by a facile papermaking strategy. Compared with bacterial cellulose (BC) and cellulose nanocrystals (CNCs), CNFs possess better dimensions and reinforcement, which enables the composite paper to exhibit better mechanical properties (tensile stress of 164.65 MPa) and electrical conductivity (11600 S·m-1), providing more possibilities for FPSs. Benefiting from these advantages, we construct an easily processable and sensitive human-interactive FPS based on a composite paper with high sensitivity (0.050 kPa-1), fast response/recovery time (158/95 ms), and exceptional stability (>1000 bending cycles), capable of responding to finger motions, voice recognition, and human pulses; through further employment as the array unit and a control circuit, the observed highly adaptive mechano-electric transformability and functions are well maintained. Overall, a facile and versatile strategy with the potential to provide clues for the fabrication of cellulose-based FPSs with outstanding performance was introduced.

2.
Carbohydr Polym ; 334: 122060, 2024 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-38553244

RESUMO

Flexible conductive hydrogels (FCHs) have attracted widespread interest as versatile monoliths that can be intricately integrated with various ingredients boasting multiple functionalities. The chemicophysical properties of FCHs cover a wide range, which significantly vary in their building blocks. However, achieving both favorable mechanical strength and high conductivity simultaneously through a facile approach remains a challenge. Herein, polyvinyl alcohol, dialdehyde cellulose nanofibrils, silver nanoparticles, borax, and tannic acid are readily "one-pot" incorporated into FCHs with great tensile stress (499 kPa), tensile strain (4591 %), and compressive stress (269 kPa) due to abundant hydrogen bonding, dynamic borate-diol bonding, and intermolecular acetalization. They also exhibit desired self-healing, generalized-adhesive, and antibacterial performances. Taking advantage of these, FCHs are further employed to support an epidermal sensor, on which remarkable strain sensitivity (gauge factor = 8.22), high-pressure sensitivity (≥ 0.258 kPa-1), and fast response (≤ 190 ms) are recorded. Its highly adaptive mechano-electric transformability and functions can be well maintained in serving as an array unit and touch screen pen. The results well addressed in this work are anticipated to pave the universal way of engineering FCHs.

3.
Carbohydr Polym ; 330: 121833, 2024 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-38368110

RESUMO

The colored and high-saline effluents during the traditional dyeing process poses serious environmental challenge. In our study, an eco-friendly cationic cellulose nano-fiber/chitosan (CCNF/CS) binary versatile auxiliary was designed for the neutral salt-free dyeing and physical enhancement of paper by mixing with pulp simply. Profiting from the rich cationic binding sites of CCNF/CS (Charge density: 3749.67 µmol/g), under near neutral conditions (pH = 6.2), the maximum adsorption capacity of anionic GL (Direct fast turquoise blue GL) on paper with 0.5 % CCNF/CS reached 1865.06 mg/g with a desirable evenness (45.5 % and 92.1 % higher than that of CCNF and NaCl group, respectively), and the dye uptake was up to 97 %. The spontaneous adsorption behavior was aligned with the pseudo-second-order and Langmuir models, with a primary physical mechanism enhanced by chemical forces. The combination of strong electronic attraction, hydrogen bonding, and n-π stacking effects granted CCNF/CS an enhanced proficiency in anionic dye adsorption. In addition, the tensile strength of the resulting paper yarn with 0.5 % CCNF/CS increased to 52.47 MPa under the optimal parameters, deriving from the CCNF/CS-induced inter-fiber cohesion. Overall, our research provided a green promising approach for the innovative neutral salt-free dyeing and mechanical enhancement of paper.

4.
Int J Biol Macromol ; 253(Pt 8): 127519, 2023 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-37866573

RESUMO

The solubility of cyclodextrin metal-organic frameworks (CD-MOFs) in aqueous media making it not suitable as sustained-release drug carrier. Here, curcumin-loaded CD-MOFs (CD-MOFs-Cur) was embedded in chitosan-graft-poly(lactic acid) (CS-LA) via a solid-in-oil-in-oil (s/o/o) emulsifying solvent evaporation method forming the sustained-release composite microspheres. At CS-LA concentration of 20 mg/mL, the composite microspheres showed good sphericity. The average particle size of CS-LA/CD-MOFs-Cur (2:1), CS-LA/CD-MOFs-Cur (4:1) and CS-LA/CD-MOFs-Cur (6:1) composite microspheres was about 9.3, 12.3 and 13.5 µm, respectively. The above composite microspheres exhibited various degradation rates and curcumin release rates. Treating in HCl solution (pH 1.2) for 120 min, the average particle size of above microspheres reduced 28.19 %, 24.34 % and 6.19 %, and curcumin released 86.23 %, 78.37 % and 52.57 %, respectively. Treating in PBS (pH 7.4) for 12 h, the average particle size of above microspheres reduced 30.56 %, 26.56 % and 10.66 %, and curcumin released 68.54 %, 54.32 % and 31.25 %, respectively. Moreover, the composite microspheres had a favorable cytocompatibility, with cell viability of higher than 90 %. These composite microspheres open novel opportunity for sustained drug release of CD-MOFs.


Assuntos
Quitosana , Curcumina , Ciclodextrinas , Estruturas Metalorgânicas , Curcumina/farmacologia , Preparações de Ação Retardada , Microesferas , Portadores de Fármacos , Tamanho da Partícula
5.
Int J Biol Macromol ; 253(Pt 2): 126723, 2023 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-37696377

RESUMO

With the increased demand for green and sustainable development, the research of advanced biomass-based carbon dots (CDs) has drawn growing attention. Herein, a one-step green solvent integration strategy-assisted solvothermal method to preparing CDs from hydrolyzed lignin and ethylenediamine (EDA) in formamide (FA) was developed. The Schiff reaction between FA and EDA contributes to the formation of -C-N groups, further inducing the high photoluminescence quantum yield (up to 42.69 %),obviously higher than NCDs prepared in H2O, EtOH and DMF systems (corresponding to H-NCDs, E-NCDs and D-NCDs, respectively). The analysis of structure, composition, photoluminescence (PL) behaviors and DFT calculations showed that F-NCDs have main blue fluorescent emission peak from 410 to 455 nm under 330-390 nm excitation due to the small sp2 structure in carbon core, and the large sp2 conjugated clusters and CO group related surface states leaded to the long wavelength emission. The F-NCDs with excellent optical properties was further used for preparing fluorescent film and invisible anti-counterfeiting ink, which exhibited outstanding fluorescence even at different temperatures and aging times. We provided a facile way for green facile preparation of lignin-based CDs and their sustainable anti-counterfeiting application.


Assuntos
Lignina , Pontos Quânticos , Carbono/química , Nitrogênio/química , Pontos Quânticos/química , Fluorescência , Corantes
6.
Carbohydr Polym ; 304: 120489, 2023 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-36641193

RESUMO

Bacterial cellulose (BC) lithium-ion batteries separators possess outstanding thermal dimensional stability and electrolyte wettability, but theirs nano diameter and high aspect ratio lead to poor porosity and pore size uniformity of dense BC separators, limiting the Li+ transmission in the separators. In this paper, chitosan (CS) with different molecular weight was grafted onto BC (named OBCS), and a high-performance OBCS separator with excellent pore structure and tunable pore size was prepared by simple suction filtration. The spacing and dispersion uniformity of OBCS were improved by the CS grafted on BC surface, thus improving the pore structure and porosity of OBCS separators. The results showed that the obtained OBCS separators not only have excellent physicochemical properties, but also exhibit higher electrochemical performances than the commercial polypropylene (PP) separator. This work provides a new feasible strategy for improving the pore structure and porosity of nanocellulose separators.


Assuntos
Quitosana , Lítio , Íons , Celulose , Fontes de Energia Elétrica
7.
Carbohydr Polym ; 283: 119135, 2022 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-35153011

RESUMO

To date, flexible pressure sensors built on silver nanowires (AgNWs) have attracted tremendous attention, owing to their versatile applications in wearable, human-interactive, health-monitoring devices. Cellulose and its derivatives, which show great promise in serving flexible pressure sensors as the desired substrate due to their natural abundance, biocompatibility, easy processibility, and low costs. Herein, we reported a rational strategy to design a silver nanowires-dual-cellulose conductive paper. Its morphology, chemical and crystal structures, thermal stability, mechanical performances, and electrical properties were carefully studied. The results suggested that good tensile properties (tensile strength ≤8.10 MPa), high electrical conductivity (≤ 1.74 × 104 S·m-1) with long-term stability, and good adhesion stability (bending cycles over 500) were obtained. Furthermore, the use of such conductive paper as substrate for versatile flexible pressure sensors was demonstrated, which exhibited fast response (~ 0.48 s) and high sensitivity, in response to finger motion, voice recognition, and human pulse, etc.


Assuntos
Celulose/química , Nanofios/química , Papel , Prata/química , Dispositivos Eletrônicos Vestíveis , Condutividade Elétrica , Humanos , Movimento (Física) , Pulso Arterial , Espectroscopia de Infravermelho com Transformada de Fourier/métodos , Resistência à Tração , Difração de Raios X/métodos
8.
Food Funct ; 12(21): 10795-10805, 2021 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-34610077

RESUMO

Curcumin has received considerable interest in functional food areas due to its variety of biological effects. However, its utilization is often limited by its insolubility and instability in aqueous solutions. Herein, curcumin was encapsulated in γ-cyclodextrin metal-organic frameworks (CD-MOFs) to achieve immediate release and rapid dissolution in water just by gentle stirring due to the dissociation of CD-MOFs. The released curcumin exhibited remarkably enhanced stability compared to its free form in aqueous solutions due to the inclusion effects of cyclodextrins. Besides, the impacts of temperature, light and gastrointestinal pH on the chemical stability of curcumin released from basic and neutral CD-MOFs were compared. The molar ratios of curcumin : γ-CD in basic CD-MOFs and neutral CD-MOFs were 1 : 1.7 and 1 : 9.8, respectively. Neutral CD-MOFs were more effective in retarding thermal and gastrointestinal degradation of curcumin because all curcumin molecules can form inclusion complexes with cyclodextrin. Basic CD-MOFs were more conducive to prolonging the half-life time of curcumin during photodegradation since its alkalinity darkened the color of curcumin solution causing lower light transmittance. Moreover, CD-MOFs exhibited higher loading and stability of curcumin due to their unique host-guest structure, than their pure cyclodextrin inclusion complex. Curcumin-loaded CD-MOFs having a fast-dissolving ability accompanied by the improved amorphous form stability of curcumin hold great potential as functional additives in instant food.


Assuntos
Curcumina/química , Ciclodextrinas/química , Compostos Organometálicos/química , Humanos , Concentração de Íons de Hidrogênio , Temperatura , Água , Difração de Raios X
9.
Carbohydr Polym ; 256: 117602, 2021 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-33483082

RESUMO

The asymmetric wetting membranes have attracted intense attention in liquid directional transportation. However, it is a huge challenge to prepare surface layer membrane for sanitary products with antibacterial and asymmetric wettability by a simple method. Herein, the bacterial cellulose grafted with chitosan (BC-CS) was used as the hydrophilic agent to modify polypropylene nonwoven fabric (PPF) substrate via easy and effective one-sided layer-by-layer spraying to prepare the asymmetric wetting and antibacterial composite membrane (BC-CS/PPF). It showed that the BC-CS/PPF had good physical properties, which was attributed to the strong and uniform physical combination between nano-sized BC-CS and PPF. The sanitary products with BC-CS/PPF surface layer, denoted as BC-CS/PPF sanitary products, also had good absorption and anti-return property. The antibacterial test revealed that BC-CS had an excellent performance against S. aureus and E. coli in the simulated application environment. Moreover, the antibacterial performance was better than that of commercial sanitary products.


Assuntos
Antibacterianos/química , Materiais Biocompatíveis/química , Celulose/química , Quitosana/química , Produtos de Higiene Menstrual , Molhabilidade , Antibacterianos/farmacologia , Escherichia coli/efeitos dos fármacos , Concentração de Íons de Hidrogênio , Interações Hidrofóbicas e Hidrofílicas , Testes de Sensibilidade Microbiana , Microscopia Eletrônica de Varredura , Polipropilenos/química , Espectroscopia de Infravermelho com Transformada de Fourier , Staphylococcus aureus/efeitos dos fármacos , Propriedades de Superfície
10.
Carbohydr Polym ; 222: 114912, 2019 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-31320083

RESUMO

Renewable and biodegradable packaging materials are desired for numerous applications. Pea starch (PS) and polylactic acid (PLA) are promising alternatives to petrochemical-based polymers except that their phase separation causes poor mechanical properties. To surmount this problem, PS/PLA films with a double-layer structure were designed. The bilayer films displayed better toughness, thermal stability and barrier capacity over those of PLA films. The incorporation of PLA on a PS layer increased water resistance and tensile strength over those of a monolayer PS film. Weak interfacial adhesion between the PS and PLA layers was revealed by Fourier transform infrared spectroscopy and scanning electron microscopy. The bilayer films reduced weight loss ratio of cherry tomatoes and extended the retention of organic acids and vitamin C. A bilayer architecture represents a promising route to develop packaging materials that display the advantageous properties of each material layer.


Assuntos
Embalagem de Alimentos/métodos , Solanum lycopersicum , Amido/química , Fenômenos Biomecânicos , Pisum sativum/metabolismo , Poliésteres/química , Resistência à Tração
11.
Carbohydr Polym ; 214: 311-316, 2019 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-30926002

RESUMO

Bacterial cellulose is an attractive material due to its outstanding biocompatibility, nanometer size and high purity, but the difficulty of dispersing has restricted its wide applications. In this study, chitosan was grafted onto bacterial cellulose by Schiff base reaction, and then obtained the nano-sized fibrils by ultrasonic dispersion process. Different concentrations of NaIO4 with various time and temperature were applied, and the maximum grafting amount of chitosan was 12.38%. The obtained products were characterized by FTIR, XRD, SEM and TEM. From the dispersibility and stability behavior research, the suspension containing chitosan was more uniform and showed better acid and temperature stability. It can also be observed in SEM and TEM images that the bacterial cellulose were dispersed into single ones and the diameter of the isolated fibril was 30-80 nm.


Assuntos
Celulose/química , Quitosana/química , Nanofibras/química , Celulose/isolamento & purificação , Gluconacetobacter xylinus/química , Concentração de Íons de Hidrogênio , Oxirredução , Bases de Schiff/síntese química , Suspensões/química , Temperatura
12.
Materials (Basel) ; 12(1)2018 Dec 20.
Artigo em Inglês | MEDLINE | ID: mdl-30577427

RESUMO

High electrolyte wettability, thermal dimensional stability, and tensile strength are prerequisites for implementing separators in practical applications. In this study, we report on the discovery of nanofibril membranes derived from various plant fibers commonly used in the papermaking industry, for low cost and higher performances than the commercially available Celgard2325 in regard to the application of separators for lithium-ion batteries. Nanofibril membranes showed water contact angles as low as 18°, negligible size change at a heating temperature of 160 °C for 120 min, and tensile strength up to 137.6 MPa. The homogenization was found to strongly contribute to these improved performances. These findings suggest that the plant fiber-derived nanofibril membranes are anticipated to be promising candidates as separators for lithium-ion batteries.

13.
Waste Manag ; 79: 729-734, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30343805

RESUMO

Biochar was produced from anaerobically digested dairy manure under different processing temperatures (300, 600 and 1000 °C). The process could transform the biomass waste to high-value-added biochar products in high efficiency as well as reduce the manure biological pollution to the environment. By the results of thermogravimetric analysis (TGA) two kinetic models (FWO and Starink) were used to evaluate the activation energy. The biochar was studied for its surface area and pore size, chemical functionality, and crystalline structure by BET analysis, Fourier transform infrared (FTIR) spectroscopy, and X-ray diffraction (XRD). More porous and channel structures were observed under higher temperature and inert gas atmosphere, as characterized by scanning electron microscopy (SEM). The biochar with tunable physicochemical properties that was produced under different temperatures may be used for soil amendment or other fields.


Assuntos
Carvão Vegetal , Esterco , Solo , Difração de Raios X
14.
Water Sci Technol ; 75(5-6): 1025-1033, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28272032

RESUMO

Herein a Mn-deposited sepiolite catalyst was obtained through a facile co-precipitation method, and then used as the heterogeneous ozonation catalysts applied to the tertiary treatment of regenerated-papermaking wastewater. During the process, the as-prepared catalyst was endowed with higher Brunauer-Emmett-Teller specific surface area of 412.3 m2/g compared to 124.6 m2/g of the natural sepiolite. Hence, in the adsorption of methylene blue, the as-prepared catalyst was observed with a very high removal rate of 96.2% although a little lower than the modified sepiolite of 97.5% in 100 min. And for practical application, the catalyst was used for treating the effluent from regenerated-papermaking industry, via a heterogeneous catalytic ozonation process. Consequently, the highest color removal rate of 99.5%, and the highest chemical oxygen demand (COD) removal efficiency of 73.4% were achieved in 20 and 30 min, respectively. As a result, the treated wastewater was more biodegradable and less toxic; the biochemical oxygen demand (BOD5)/COD value could reach 0.41. Moreover, the catalyst showed superior stability at successive ozonation runs. The main possible reaction pathway is also presented. The results indicate that catalytic ozonation was proved to be effective when Mn/sepiolite was used as catalysts applied to the advanced treatment of regenerated-papermaking wastewater.


Assuntos
Silicatos de Magnésio/química , Ozônio/química , Papel , Reciclagem , Águas Residuárias , Purificação da Água/métodos , Adsorção , Análise da Demanda Biológica de Oxigênio , Catálise , Cor , Compostos Orgânicos/isolamento & purificação , Poluentes Químicos da Água/isolamento & purificação , Difração de Raios X
15.
Bioresour Technol ; 234: 8-14, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28315605

RESUMO

Herein, bacterial cellulose (BC) was synthesized by acetobacter xylinum via organic acid pre-hydrolysis liquor of agricultural corn stalk used as carbon source. Acetic acid was applied to pretreat the corn stalk, then, the prehydrolysate was detoxified by sequential steps of activated carbon and ion exchange resin treatment prior to use as carbon source to cultivate acetobacter xylinum. Moreover, the recovery of acetic acid was achieved for facilitating the reduction of cost. The results revealed that the combination method of detoxification treatment was very effective for synthesis of BC, yield could be up to 2.86g/L. SEM analysis showed that the diameter size of BC between 20 and 70mm. In summary, the process that bacterial cellulose was biosynthesized via prehydrolysate from agricultural corn stalk used as carbon source is feasible, and the ability to recover organic acid make it economical, sustainable and green, which fits well into the biorefinery concept.


Assuntos
Zea mays , Ácido Acético , Carbono , Celulose , Gluconacetobacter xylinus , Hidrólise
16.
Carbohydr Polym ; 151: 834-840, 2016 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-27474631

RESUMO

Immobilized silver nano-particles (Ag NPs) possess excellent antimicrobial properties due to their unique surface characteristics. In this paper, immobilized silver nano-particles were synthesized in the presence of chitin nano-crystals (CNC) based on the Tollens mechanism (reduction of silver ion by aldehydes in the chitosan oligosaccharides (COS)) under microwave-assisted conditions. The prepared Ag NPs-loaded CNC nano-composites were then applied onto the paper surface via coating for the preparation of antibacterial paper. Fourier transform infrared (FT-IR) and X-ray diffraction (XRD) results confirmed that the Ag NPs were immobilized onto the CNC. The transmission electron microscope (TEM) and scanning electron microscopy (SEM) results further revealed that the spherical Ag NPs (5-12nm) were well dispersed on the surface of CNC. The coated paper made from the Ag NPs-loaded CNC nano-composites exhibited a high effectiveness of the antibacterial activity against E. coli or S. aureus.


Assuntos
Antibacterianos/química , Antibacterianos/farmacologia , Celulose/química , Quitina/química , Nanopartículas Metálicas/química , Papel , Prata/química , Escherichia coli/efeitos dos fármacos , Micro-Ondas , Nanotecnologia , Staphylococcus aureus/efeitos dos fármacos , Propriedades de Superfície , Água/química
17.
Carbohydr Polym ; 127: 400-6, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25965499

RESUMO

Commercial bleached softwood kraft pulp was mechanically fibrillated by a PFI-mill with beating revolution from 5000 to 30,000 r. The extent of fibrillating on the pulp was evaluated by beating degree, fiber morphological properties (fiber length, width, coarseness and curls index), water retention value (WRV) and physical properties of paper made from the pulp. Depth beating process significantly affected the pulp fibrillations as showed by the decreased fiber length and width as well as the SEM analysis, but the effects were limited after beating revolution of 15,000. Depth beating process also improved the total internal pore and inter-fibril surface areas as shown by the increased WRV values. Substrate enzymatic digestibility (SED) of beaten pulp at 5000 revolutions could reach 95% at cellulase loading of 15 FPU/g of glucan. After the enzymatic hydrolysis, the size of the pulp residues was reduced to micro-scale, and a relative uniform size distribution of the residues appeared at 10,000 r beating revolution.


Assuntos
Celulase/metabolismo , Glucanos/metabolismo , Papel , Madeira/metabolismo , Celulase/química , Glucanos/química , Hidrólise , Tamanho da Partícula , Propriedades de Superfície , Madeira/química
18.
Int J Biol Macromol ; 75: 378-87, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25666853

RESUMO

With the aim to discover chitosan derivatives with enhanced antibacterial activity and good water solubility compared with natural chitosan, a novel O-quaternary ammonium N-acyl thiourea chitosan (OQCATUCS) bearing double antibacterial groups with different degrees of substitution has been synthesized. The derivative was characterized by FTIR, (13)C NMR, elemental analysis, XRD, TGA and zeta potential analysis. Water solubility was also investigated. The antimicrobial activities of chitosan and its derivatives were investigated by assessing the mortality rates of Staphyloccocus aureus, Escherichia coli, Aspergillus niger, Pseudomonas aeruginosa and Bacillus subtilis. The order of antibacterial activities was O-quaternary ammonium N-acyl thiourea chitosan (OQCATUCS)>O-quaternary ammonium chitosan (OQCS)>chitosan (CS). The zeta potential and antibacterial results indicated that the introduced quaternary ammonium and thiourea groups increased the positive charge of chitosan derivative, thereby enhanced its antibacterial activity. The mechanism of chitosan derivatives against E. coli and S. aureus was evaluated via analyzing integrity of cell membranes and transmission electron microscopy data. These results demonstrated that OQCATUCS killed the bacteria via disrupting the cell membrane.


Assuntos
Antibacterianos/síntese química , Antibacterianos/farmacologia , Quitosana/síntese química , Quitosana/farmacologia , Antibacterianos/química , Bactérias/efeitos dos fármacos , Bactérias/ultraestrutura , Espectroscopia de Ressonância Magnética Nuclear de Carbono-13 , Membrana Celular/efeitos dos fármacos , Membrana Celular/metabolismo , Quitosana/química , Fungos/efeitos dos fármacos , Concentração de Íons de Hidrogênio , Testes de Sensibilidade Microbiana , Compostos de Amônio Quaternário/síntese química , Compostos de Amônio Quaternário/química , Compostos de Amônio Quaternário/farmacologia , Solubilidade , Espectroscopia de Infravermelho com Transformada de Fourier , Eletricidade Estática , Termogravimetria , Tioureia/síntese química , Tioureia/química , Tioureia/farmacologia , Água , Difração de Raios X
19.
Carbohydr Polym ; 103: 510-9, 2014 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-24528761

RESUMO

Ethyl cellulose macroinitiator was firstly synthesized by direct acylation of ethyl cellulose with 2-bromopropionyl bromide in a room temperature. And a light-responsive triblock copolymer of ethyl cellulose-g-poly(2-hydroxyethyl methacrylate)-g-poly(spiropyran ether methacrylate) (EC-g-PHEMA-g-PSPMA) was prepared by atom transfer radial polymerization. The amphiphilic structure of the copolymer enabled it to aggregate into spherical micelles in aqueous solution with an average diameter of 100 nm. The micelles exhibited light-responsive performance because of the SPMA monomer. The hydrophobic side chain of PSPMA became hydrophilic under UV light, which decreased the average size of the micelles. Additionally, the diameters of the micelles can be recovered when subsequently irradiated with visible light. The loading and light-triggered release profiles of model drugs were also investigated, and results showed that the release behavior can be controlled by changing the light wavelength.


Assuntos
Preparações Farmacêuticas/química , Polímeros/química , Sistemas de Liberação de Medicamentos , Interações Hidrofóbicas e Hidrofílicas , Micelas , Estrutura Molecular , Tamanho da Partícula , Polímeros/síntese química , Propriedades de Superfície , Tensoativos/síntese química , Tensoativos/química
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