1.
Beilstein J Org Chem
; 10: 2286-92, 2014.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25298796
RESUMO
An efficient one-pot tandem cyclization/[3 + 2] cycloaddition reaction of N'-(2-alkynylbenzylidene)hydrazides with ethyl 4,4,4-trifluorobut-2-ynoate under silver triflate-catalyzed or electrophile-mediated conditions is described. Various trifluoromethylated pyrazolo[5,1-a]isoquinolines were afforded in moderate to excellent yield by this developed method.