RESUMO
A total of 17 isolates of Stachybotrys atra isolated from various parts of Hungary and Czechoslovakia were grown on rice, and the toxin production of each isolate was analyzed by high-performance liquid chromatography. Of the 17 isolates, 14 produced macrocyclic trichothecenes (satratoxins F, G, and H, roridin E, and verrucarin J) as well as trichoverrols A and B. Most isolates produced satratoxins G and H in higher quantities than the other trichothecenes. The yield (in milligrams) of trichothecenes produced by one isolate grown on 800 g of rice was as follows: roridin E, 12; satratoxin F, 10; satratoxin G, 75; satratoxin H, 100; trichoverrol A, 15; and trichoverrol B, 30.
Assuntos
Fungos Mitospóricos/metabolismo , Sesquiterpenos/biossíntese , Stachybotrys/metabolismo , Tricotecenos/biossíntese , Cromatografia Líquida de Alta Pressão , Tchecoslováquia , Hungria , OryzaRESUMO
Five plant-pathogenic isolates of Myrothecium roridum from Florida produced only simple trichothecenes rather than the usual macrocyclic trichothecenes. The major metabolite was 7 alpha-hydroxytrichodermol.
Assuntos
Fungos Mitospóricos/crescimento & desenvolvimento , Sesquiterpenos/isolamento & purificação , Fermentação , Espectroscopia de Ressonância Magnética , Espectrometria de Massas , Modelos Moleculares , Conformação Molecular , OryzaRESUMO
Verrucarol was obtained from a simple procedure that involved the hydrolysis of a crude extract of a culture of Myrothecium verrucaria ATCC 24571.
