Color Vision Deficiency and Functional Disorders Among Israeli Male Adolescents Between 2007 and 2013.

Color vision deficiency has been associated with educational difficulties among male children, as well as attention-deficit hyperactivity disorder (ADHD). We examined the association of color vision deficiency with functional conditions, including ADHD, irritable bowel syndrome, enuresis and somatoform disorders, in a large population of male adolescents. We included all Israeli male adolescents that underwent medical and cognitive examinations during conscription between the years 2007 and 2013. The prevalence of ADHD, irritable bowel syndrome, enuresis, and somatoform disorders among color vision deficiency patients was compared to a control group. The study included 305 964 males aging 17 ± 0.6, of which 7584 (2.5%) had color vision deficiency. Using a multivariable analysis, the probability for irritable bowel syndrome, enuresis, and somatoform disorders among color vision deficiency patients was increased by 1.41, 1.94, and 3.87, respectively (P < .05). No significant association was found between ADHD and color vision deficiency. Color vision abnormalities are associated with functional disorders in male adolescents, including irritable bowel syndrome, enuresis, and somatoform disorders.

Is Male Migraine Associated With Color Vision Deficiency? Findings Among Israeli Adolescents Between 2007 and 2013.

OBJECTIVE: Accumulating clinical and experimental evidence has shown that migraine patients tend to suffer from color vision abnormalities. The aim of this study was to examine whether color vision deficiency is associated with male migraine in a large population of adolescents. METHODS: The study population included all Israeli male adolescents who underwent medical and cognitive examinations as part of their recruiting process between the years 2007 and 2013. Migraine prevalence among patients with color vision deficiency was compared to that of males without substantial color vision abnormalities. RESULTS: The study population included 305 964 male adolescents at the age of 17 ± 0.6, of whom 7584 (2.5%) had color vision deficiency, as determined by the Farnsworth Panel D-15 color blindness test. Males with color vision deficiency had a 32% increased prevalence of migraine as compared with the control group (odds ratio 1.32, 95% confidence interval 1.18-1.48, P < .001), after adjusting for multiple variables. CONCLUSIONS: The authors found an association between color vision deficiency and migraine in male adolescents. The study results lay the basis for further research into male migraine, as well as the visual aspects of migraine.