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Gan To Kagaku Ryoho ; 48(7): 939-943, 2021 Jul.
Artigo em Japonês | MEDLINE | ID: mdl-34267032

RESUMO

In recent years, attention has been focused on environmental exposure of anticancer drugs, and guidelines for occupational exposure measures in cancer drug therapy have been created in Japan. Exposure measures related to the preparation and administration of anticancer drugs are being standardized. Although exposure measures have been implemented for the preparation and administration of the infusion pump(IP)used for continuous fluorouracil administration for 46-hour in FOLFOX and FOLFIRI therapies, which are standard chemotherapies for colorectal cancer, needle-removal procedures after the end of administration have not been investigated. Therefore, in this study, we investigated anticancer drug exposure at the time of IP needle removal to establish a safe needle-removal procedure from the viewpoint of anticancer drug exposure countermeasures. The results suggest that the IP's clamp lock position and the pulsing flush of the Huber needle may reduce antineoplastic exposure. In the future, we would like to consider this an educational method for needle-removal techniques.


Assuntos
Antineoplásicos , Neoplasias Colorretais , Antineoplásicos/uso terapêutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Camptotecina/uso terapêutico , Neoplasias Colorretais/tratamento farmacológico , Fluoruracila/uso terapêutico , Humanos , Bombas de Infusão , Japão , Leucovorina/uso terapêutico , Compostos Organoplatínicos/uso terapêutico
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