RESUMO
Evidence here cited underlies resolutions at international meetings to initiate a chronobiology project for health improvement. This project demonstrates expeditiously the feasibility and the health benefits of incorporating chronomedical considerations in the diagnosis, treatment, and prevention of one (or a few closely related) vascular (and oncological) diseases, that have high awareness and importance in the public perspective. Thereby, chronomedicine should become a mainstream basic and applied speciality leading to continual improvement in national/international health status. Reference data obtained for health care can also serve to give a better understanding of the relationship between the terrestrial biosphere and cosmoi near and far.
Assuntos
Pressão Sanguínea , Atenção à Saúde , Frequência Cardíaca , Voo Espacial , Humanos , PesquisaRESUMO
Meropenem was used in the treatment of 15 newborns (8 preterm) with sepsis, pneumonia or meningitis by intravenous infusion of 15-20 mg/kg daily divided to 3 equal doses. Clinical improvement was achieved in all the cases. No side effects were recorded.
Assuntos
Infecções Bacterianas/tratamento farmacológico , Doenças do Prematuro/tratamento farmacológico , Tienamicinas/uso terapêutico , Relação Dose-Resposta a Droga , Humanos , Recém-Nascido , Meningites Bacterianas/tratamento farmacológico , Meropeném , Pneumonia Bacteriana/tratamento farmacológico , Sepse/tratamento farmacológicoRESUMO
In several human adults, certain solar activity rhythms may influence an about 7-day rhythm in heart rate. When no about-weekly feature was found in the rate of change in sunspot area, a measure of solar activity, the double amplitude of a circadian heart rate rhythm, approximated by the fit of a 7-day cosine curve, was lower, as was heart rate corresponds to about-weekly features in solar activity and/or relates to a sunspot cycle.