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2.
Case Rep Obstet Gynecol ; 2015: 792412, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25648983

RESUMO

Multiple large polypoid lesions with exophytic appearance occurring in anal and perineal region as a result of human papilloma virus (HPV) infection are referred to as giant condyloma acuminatum (GCA). The conventional treatment of these lesions involves the use of surgical excision, laser, electrocautery, and/or application of trichloroacetic acid. A 28-year-old primigravid patient at 22 weeks of pregnancy presented to the hospital complaining of vaginal bleeding and palpable mass in the vulva. The physical examination revealed a 60 × 35 mm broad-based, fragile, and patchy hemorrhagic polypoid lesion originating 1 cm below the clitoris and completely occupying urethral orifice and partially occluding vaginal vestibule. The patient underwent excision of GCA in the midtrimester using an ultrasonic thermal scalpel (Harmonic Scalpel) without any additional treatment and subsequently delivered a single live healthy baby. The excision of GCA occurring during pregnancy using Harmonic Scalpel can be regarded as a new successful method. Prospective, randomized, and controlled studies are warranted in order to provide clear evidence of the efficiency and safety of HS in the treatment of GCA.

3.
Cutan Ocul Toxicol ; 33(4): 339-41, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24641119

RESUMO

A 27-year-old male patient presented with a maculopapular eruption on the flexural areas and buttocks after using oral ketoconazole. The patient was diagnosed with drug-induced baboon syndrome based on his history, which included prior sensitivity to topical ketoconazole, a physical examination, and histopathological findings. Baboon syndrome is a drug- or contact allergen-related maculopapular eruption that typically involves the flexural and gluteal areas. To the best of our knowledge, this is the first reported case of ketoconazole-induced baboon syndrome in the English literature.


Assuntos
Antifúngicos/efeitos adversos , Toxidermias/patologia , Cetoconazol/efeitos adversos , Administração Tópica , Adulto , Antifúngicos/administração & dosagem , Antifúngicos/uso terapêutico , Nádegas , Eritema/induzido quimicamente , Eritema/patologia , Humanos , Cetoconazol/administração & dosagem , Cetoconazol/uso terapêutico , Masculino , Pele/patologia , Síndrome , Tinha dos Pés/complicações , Tinha dos Pés/tratamento farmacológico
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