Flexible iontronics with super stretchability, toughness and enhanced conductivity based on collaborative design of high-entropy topology and multivalent ion-dipole interactions.

All-solid-state ionic conductive elastomers (ASSICEs) are emerging as a promising alternative to hydrogels and ionogels in flexible electronics. Nevertheless, the synthesis of ASSICEs with concomitant mechanical robustness, superior ionic conductivity, and cost-effective recyclability poses a formidable challenge, primarily attributed to the inherent contradiction between mechanical strength and ionic conductivity. Herein, we present a collaborative design of high-entropy topological network and multivalent ion-dipole interaction for ASSICEs, and successfully mitigate the contradiction between mechanical robustness and ionic conductivity. Benefiting from the synergistic effect of this design, the coordination, de-coordination, and intrachain transfer of Li+ are effectively boomed. The resultant ASSICEs display exceptional mechanical robustness (breaking strength: 7.45 MPa, fracture elongation: 2621%, toughness: 107.19 MJ m-3) and impressive ionic conductivity (1.15 × 10-2 S m-1 at 25 °C). Furthermore, these ASSICEs exhibit excellent environmental stability (fracture elongation exceeding 1400% at 50 °C or -60 °C) and recyclability. Significantly, the application of these ASSICEs in a strain sensor highlights their potential in various fields, including human-interface communication, aerospace vacuum measurement, and medical balloon monitoring.

Phase-separated porous nanocomposite with ultralow percolation threshold for wireless bioelectronics.

Realizing the full potential of stretchable bioelectronics in wearables, biomedical implants and soft robotics necessitates conductive elastic composites that are intrinsically soft, highly conductive and strain resilient. However, existing composites usually compromise electrical durability and performance due to disrupted conductive paths under strain and rely heavily on a high content of conductive filler. Here we present an in situ phase-separation method that facilitates microscale silver nanowire assembly and creates self-organized percolation networks on pore surfaces. The resultant nanocomposites are highly conductive, strain insensitive and fatigue tolerant, while minimizing filler usage. Their resilience is rooted in multiscale porous polymer matrices that dissipate stress and rigid conductive fillers adapting to strain-induced geometry changes. Notably, the presence of porous microstructures reduces the percolation threshold (Vc = 0.00062) by 48-fold and suppresses electrical degradation even under strains exceeding 600%. Theoretical calculations yield results that are quantitatively consistent with experimental findings. By pairing these nanocomposites with near-field communication technologies, we have demonstrated stretchable wireless power and data transmission solutions that are ideal for both skin-interfaced and implanted bioelectronics. The systems enable battery-free wireless powering and sensing of a range of sweat biomarkers-with less than 10% performance variation even at 50% strain. Ultimately, our strategy offers expansive material options for diverse applications.

Multimodal Wireless Wound Sensors via Higher-Order Parity-Time Symmetry.

Chronic wounds have emerged as a significant healthcare burden, affecting millions of patients worldwide and presenting a substantial challenge to healthcare systems. The diagnosis and management of chronic wounds are notably intricate, with inappropriate management contributing significantly to the amputation of limbs. In this work, we propose a compact, wireless, battery-free, and multimodal wound monitoring system to facilitate timely and effective wound treatment. The design of this monitoring system draws on the principles of higher-order parity-time symmetry, which incorporates spatially balanced gain, neutral, and loss, embodied by an active -RLC reader, an LC intermediator, and a passive RLC sensor, respectively. Our experimental results demonstrate that this wireless wound sensor can detect temperature (T), relative humidity (RH), pressure (P), and pH with exceptional sensitivity and robustness, which are critical biomarkers for assessing wound healing status. Our in vitro experiments further validate the reliable sensing performance of the wound sensor on human skin and fish. This multifunctional monitoring system may provide a promising solution for the development of futuristic wearable sensors and integrated biomedical microsystems.

Electromagnetically unclonable functions generated by non-Hermitian absorber-emitter.

Physically unclonable functions (PUFs) are a class of hardware-specific security primitives based on secret keys extracted from integrated circuits, which can protect important information against cyberattacks and reverse engineering. Here, we put forward an emerging type of PUF in the electromagnetic domain by virtue of the self-dual absorber-emitter singularity that uniquely exists in the non-Hermitian parity-time (PT)-symmetric structures. At this self-dual singular point, the reconfigurable emissive and absorptive properties with order-of-magnitude differences in scattered power can respond sensitively to admittance or phase perturbations caused by, for example, manufacturing imperfectness. Consequently, the entropy sourced from inevitable manufacturing variations can be amplified, yielding excellent PUF security metrics in terms of randomness and uniqueness. We show that this electromagnetic PUF can be robust against machine learning-assisted attacks based on the Fourier regression and generative adversarial network. Moreover, the proposed PUF concept is wavelength-scalable in radio frequency, terahertz, infrared, and optical systems, paving a promising avenue toward applications of cryptography and encryption.

Review on Recent Advances and Applications of Passive Harmonic RFID Systems.

Radio frequency identification (RFID) has gained significant attention because it provides a highly versatile platform for identifying, tracking, and monitoring objects. An emerging trend in this technology is the use of nonlinear RFID, such as passive harmonic tags, which have been demonstrated to be effective against clutters, echoes, crosstalk, and other electromagnetic interferences. This article presents a comprehensive review of recent advances and applications of passive harmonic RFIDs and integrated systems. A passive harmonic RFID exploits the frequency orthogonality of the transmitted (fundamental tone) and received (harmonics) radio-frequency (RF) signals to enable robust interrogation in noisy and cluttered environments, not possible with traditional passive linear RFIDs. This review article evaluates passive harmonic RFID systems in comparison to traditional systems and highlights their pros and cons. Several state-of-the-art chipless and chip-based harmonic RFIDs are presented, and their novel applications in identification, tracking, sensing, and biotelemetry are discussed. The review summarizes the key successes and challenges of passive harmonic RFID systems and provides insights into their future development, implementation, and optimization.

Recent Advances in Nanomaterials Used for Wearable Electronics.

In recent decades, thriving Internet of Things (IoT) technology has had a profound impact on people's lifestyles through extensive information interaction between humans and intelligent devices. One promising application of IoT is the continuous, real-time monitoring and analysis of body or environmental information by devices worn on or implanted inside the body. This research area, commonly referred to as wearable electronics or wearables, represents a new and rapidly expanding interdisciplinary field. Wearable electronics are devices with specific electronic functions that must be flexible and stretchable. Various novel materials have been proposed in recent years to meet the technical challenges posed by this field, which exhibit significant potential for use in different wearable applications. This article reviews recent progress in the development of emerging nanomaterial-based wearable electronics, with a specific focus on their flexible substrates, conductors, and transducers. Additionally, we discuss the current state-of-the-art applications of nanomaterial-based wearable electronics and provide an outlook on future research directions in this field.

Materials, Designs, and Implementations of Wearable Antennas and Circuits for Biomedical Applications: A Review.

The intersection of biomedicine and radio frequency (RF) engineering has fundamentally transformed self-health monitoring by leveraging soft and wearable electronic devices. This paradigm shift presents a critical challenge, requiring these devices and systems to possess exceptional flexibility, biocompatibility, and functionality. To meet these requirements, traditional electronic systems, such as sensors and antennas made from rigid and bulky materials, must be adapted through material science and schematic design. Notably, in recent years, extensive research efforts have focused on this field, and this review article will concentrate on recent advancements. We will explore the traditional/emerging materials for highly flexible and electrically efficient wearable electronics, followed by systematic designs for improved functionality and performance. Additionally, we will briefly overview several remarkable applications of wearable electronics in biomedical sensing. Finally, we provide an outlook on potential future directions in this developing area.

In-Vitro Demonstration of Ultra-Reliable, Wireless and Batteryless Implanted Intracranial Sensors Operated on Loci of Exceptional Points.

Vital signal monitoring, such as pulse, respiration rate, intra-organ and intra-vascular pressure, can provide important information for determination of clinic diagnosis, treatments, and surgical protocols. Nowadays, micromachined bioimplants, equipped with antennas for converting bio-signals to modulated radio transmissions, may allow remote continuous monitoring of patients' vital signs. Yet, current passive biotelemetry techniques usually suffer from poor signal reproducibility and robustness in light of inevitable misalignment between transmitting and receiving antennas. Here, we seek to address this long-existing challenge and to robustly acquire information from a passive wireless intracranial pressure (or brain pressure) sensor by introducing a novel, high-performance biotelemetry system. In spite of variable inductive links, this biotelemetry system may have absolute accuracy by leveraging the uniqueness of loci of exceptional points (EPs) in non-Hermitian radio-frequency (RF) electronic systems with parity-time (PT) symmetry. Our in-vitro experimental demonstration shows that the proposed intracranial (ICP) monitoring system can provide a sub-mmHg resolution in the ICP range of 0-20 mmHg and ultra-robust wireless data acquisition against the misalignment-induced weakening of inductive link. Our results could provide a practical pathway toward reliable, real-time wireless monitoring of ICP, and other vital signals generated by bio-implants and wearables.

A Breathable, Reusable, and Zero-Power Smart Face Mask for Wireless Cough and Mask-Wearing Monitoring.

We herein introduce a lightweight and zero-power smart face mask, capable of wirelessly monitoring coughs in real time and identifying proper mask wearing in public places during a pandemic. The smart face mask relies on the compact, battery-free radio frequency (RF) harmonic transponder, which is attached to the inner layer of the mask for detecting its separation from the face. Specifically, the RF transponder composed of miniature antennas and passive frequency multiplier is made of spray-printed silver nanowires (AgNWs) coated with a poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) passivation layer and the recently discovered multiscale porous polystyrene-block-poly(ethylene-ran-butylene)-block-polystyrene (SEBS) substrate. Unlike conventional on-chip or on-board wireless sensors, the SEBS-AgNWs/PEDOT:PSS-based RF transponder is lightweight, stretchable, breathable, and comfortable. In addition, this wireless device has excellent resilience and robustness in long-term and repeated usages (i.e., repeated placement and removal of the soft transponder on the mask). We foresee that this wireless smart face mask, providing simultaneous cough and mask-wearing monitoring, may mitigate virus-transmissive events by tracking the potential contagious person and identifying mask-wearing conditions. Moreover, the ability to wirelessly assess cough frequencies may improve diagnosis accuracy for dealing with several diseases, such as chronic obstructive pulmonary disease.

PTX-symmetric metasurfaces for sensing applications.

In this paper, we introduce an ultra-sensitive optical sensing platform based on the parity-time-reciprocal scaling (PTX)-symmetric non-Hermitian metasurfaces, which leverage exotic singularities, such as the exceptional point (EP) and the coherent perfect absorber-laser (CPAL) point, to significantly enhance the sensitivity and detectability of photonic sensors. We theoretically studied scattering properties and physical limitations of the PTX-symmetric metasurface sensing systems with an asymmetric, unbalanced gain-loss profile. The PTX-symmetric metasurfaces can exhibit similar scattering properties as their PT-symmetric counterparts at singular points, while achieving a higher sensitivity and a larger modulation depth, possible with the reciprocal-scaling factor (i.e., X transformation). Specifically, with the optimal reciprocal-scaling factor or near-zero phase offset, the proposed PTX-symmetric metasurface sensors operating around the EP or CPAL point may achieve an over 100 dB modulation depth, thus paving a promising route toward the detection of small-scale perturbations caused by, for example, molecular, gaseous, and biochemical surface adsorbates.

A highly sensitive biosensor based on Au NPs/rGO-PAMAM-Fc nanomaterials for detection of cholesterol.

OBJECTIVE: This study aimed to construct a biosensor using Au nanoparticles (Au NPs) and reduced graphene-polyamide-amine-ferrocene (rGO-PAMAM-Fc) nanomaterials designed for rapid and sensitive detection of cholesterol. MATERIALS AND METHODS: In this study, a highly sensitive biosensor based on Au NPs/ rGO-PAMAM-Fc nanomaterials was manufactured for detection of cholesterol. The rGO-PAMAM-Fc and Au NPs were modified on the surface of the electrode and then coated with cholesterol oxidase (ChOx) and cholesterol esterase (ChEt) to develop the ChOx&ChEt/Au NPs/rGO-PAMAM-Fc biosensor. RESULTS: The capability of rGO-PAMAM-Fc nanomaterials in fabricating a more efficient biosensor was validated through stability, selectivity and reproducibility checks. Under optimal conditions, the newly developed biosensor showed a linear relationship with logarithm of cholesterol concentration from 0.0004 to 15.36 mM (R 2=0.9986), and a low detection limit of 2 nM was obtained at the signal/noise ratio of 3. CONCLUSION: The ChOx&ChEt/Au NPs/rGO-PAMAM-Fc biosensor was successfully applied for the measurement of cholesterol in human serum, which implies that the biosensor has a potential application in clinical diagnostics.