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J Korean Med Sci ; 29(10): 1432-5, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25368499

RESUMO

Metastasis to the primary thyroid carcinoma is extremely rare. We report here a case of colonic adenocarcinoma metastasis to medullary thyroid carcinoma in a 53-yr old man with a history of colon cancer. He showed a nodular lesion, suggesting malignancy in the thyroid gland, in a follow-up examination after colon cancer surgery. Fine needle aspiration biopsy (FNAB) of the thyroid gland showed tumor cell clusters, which was suspected to be medullary thyroid carcinoma (MTC). The patient underwent a total thyroidectomy. Using several specific immunohistochemical stains, the patient was diagnosed with colonic adenocarcinoma metastasis to MTC. To the best of our knowledge, the present patient is the first case of colonic adenocarcinoma metastasizing to MTC. Although tumor-tumor metastasis to primary thyroid carcinoma is very rare, we still should consider metastasis to the thyroid gland, when a patient with a history of other malignancy presents with a new thyroid finding.


Assuntos
Carcinoma Medular/secundário , Neoplasias do Colo/patologia , Segunda Neoplasia Primária/diagnóstico , Neoplasias da Glândula Tireoide/secundário , Adenocarcinoma/patologia , Adenocarcinoma/cirurgia , Biópsia por Agulha Fina , Carcinoma Medular/diagnóstico , Carcinoma Medular/diagnóstico por imagem , Carcinoma Neuroendócrino , Neoplasias do Colo/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Glândula Tireoide/patologia , Neoplasias da Glândula Tireoide/diagnóstico , Neoplasias da Glândula Tireoide/diagnóstico por imagem , Nódulo da Glândula Tireoide/diagnóstico
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