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Dermatol Online J ; 22(4)2016 Apr 18.
Artigo em Inglês | MEDLINE | ID: mdl-27617464

RESUMO

Acral pseudolymphomatous angiokeratoma of children (APACHE) is a rare form of cutaneous pseudolymphoma characterized byangiomatous papules with a predilection for the acral regions of children. Classically, a dense dermal lymphocytic infiltrate composed of both T and B cells is seen in histological specimens, together with prominent vessels lined by plump endothelial cells. Increasing evidence suggests that this condition is neither necessarily acral, pseudolymphomatous, nor angiokeratomatous. It may not always be a pediatric disease. Therefore, the correctness of its nomenclature has been questioned. Herein, we report threecases whose clinical and histological features were consistent with the diagnosis of APACHE. To our knowledge, this is the first report of APACHE from Southeast Asia. We also discuss why we believe "APACHE" to be a misnomer and support "papular angiolymphoid hyperplasia" as a more accurate and encompassing term. In addition, we illustrate a case with significant overlapping features with lymphoplasmacytic plaque in children, suggesting that both entities may exist on a clinical andhistological spectrum.


Assuntos
Angioceratoma/patologia , Hiperplasia Angiolinfoide com Eosinofilia/patologia , Pseudolinfoma/patologia , Neoplasias Cutâneas/patologia , Criança , Feminino , Humanos , Masculino , Singapura , Dermatopatias/patologia , Terminologia como Assunto , Adulto Jovem
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