RESUMO
This audit explores readmissions into inpatient services for adults with intellectual disabilities, using two case studies. Thirteen semi-structured interviews were conducted with professionals, to gain a multidisciplinary perspective, between February and March 2010, and analysed using thematic analysis. The main themes found in case study 1 were: narrow focus, environment, communication, early discharge, and deterioration. The main themes found in case study 2 were: deterioration, communication, discharge too soon, and environment. The aims of the audit were to contribute to good practice and provide a better understanding of readmission within our services.
Assuntos
Pessoas com Deficiência/reabilitação , Deficiência Intelectual/terapia , Readmissão do Paciente , Pesquisa Qualitativa , Adulto , Pessoas com Deficiência/psicologia , Humanos , Deficiência Intelectual/psicologia , Deficiência Intelectual/reabilitação , Entrevista Psicológica , Masculino , Auditoria Médica/métodos , Readmissão do Paciente/normas , Índice de Gravidade de DoençaRESUMO
Effects of agmatine, an endogenous metabolite formed by decarboxylation of L-arginine, on ethanol-induced gastric mucosal injury were investigated in rats. Agmatine at 1 and 10 mg/kg i.p doses significantly increased ethanol-induced gastric mucosal injury. This effect of agmatine was abolished completely by pretreatment with idazoxan, an imidazoline receptor-antagonist and alpha2 receptor- antagonist, (0.5 mg/kg i.p), partly by yohimbine, an alpha2 receptor- antagonist, (1 mg/kg i.p) but not by L-arginine, a precursor of nitric oxide, (500 mg/kg i.p). Our results suggest that agmatine had a potent ulcerogenic effect mediated, at least in part, by both alpha2-adrenoceptors and imidazoline receptors.