[Opacification of hydrophilic intraocular lens after multiple injections of bevacizumab]. / Eintrübung einer hydrophilen Intraokularlinse nach multiplen Bevacizumab-Injektionen.

In the literature various causes of opacification of hydrophilic lenses have been described. Pronounced opacity is a complication that must be taken seriously because it can lead to explantation or exchange of the intraocular lens (IOL). The calcification of hydrophilic IOLs is often made responsible for an explantation. Despite the rapidly increasing number of intravitreal injections, they have so far not been associated with opacification of lenses. This article reports on a female patient where opacification of the hydrophilic lens was obviously associated with multiple intravitreal injections over several years. It involved a secondary calcification with calcium phosphate deposition directly under the surface of the IOL. Possible pathomechanisms are discussed. Due to the increasing number of intravitreal injections the association with IOL opacity should be further evaluated in the future. Generally, with hydrophilic lens materials it must be taken into consideration that these can become opaque following diverse interventions.

[Optical quality of three trifocal intraocular lens models : An optical bench comparison]. / Optische Qualität dreier trifokaler Intraokularlinsenmodelle : Vergleich an der optischen Bank.

BACKGROUND: Knowledge of the optical quality of different trifocal intraocular lenses (IOL) is important in customized patient care. OBJECTIVE: Different trifocal IOL were compared regarding their optical quality. MATERIALS AND METHODS: We analyzed the FineVision (PhysIOL, Liège, Belgium), the AT LISA tri 839MP (Zeiss, Oberkochen, Germany), and the AcrySofIQ PanOptix (Alcon, Fort Worth, TX, USA) with a power of +21D for the distance using the OptiSpheric IOL PRO optical bench (Trioptics, Wedel, Germany). The additions for the near and intermediate distances were as follows: +3.5D/+1.75D (FineVision), +3.33D/+1.66D (AT LISA tri), and + 3,25D/+ 2,17D (PanOptix). We evaluated the modulation transfer function (MTF) at a spatial frequency of 50lp/mm and the Strehl ratio using 3­ (photopic) and 4.5-mm (mesopic) apertures. RESULTS: The MTF at 50 lp/mm (FineVision/AT Lisa tri/PanOptix) at the far focus was 0.373/0.399/0.400 (3-mm aperture) and 0.512/0.311/0.243 (4.5-mm aperture). At the intermediate focus, the MTF was 0.162/0.147/0.153 (3-mm aperture) and 0.092/0.125/0.137 (4.5-mm aperture). The MTF at the near focus was 0.229/0.192/0.404 (3-mm aperture) and 0.217/0.212/0.169 (4.5-mm aperture). The Strehl ratio was 0.335/0.298/0.370 (3-mm aperture) and 0.243/0.180/0.270 (4.5-mm aperture) at the far focus. At intermediate distances, the Strehl ratio was 0.189/0.185/0.162 (3-mm aperture) and 0.099/0.097/0.114 (4.5-mm aperture). The Strehl ratio was 0.305/0.283/0.464 (3-mm aperture) and 0.177/0.181/0.155 (4.5-mm aperture) at the near focus. CONCLUSION: Evaluation of the three trifocal IOL models at the optical bench could show distinct peaks at the far, intermediate, and near focus. The results were comparable in terms of optical performance.