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【Objective】 To evaluate the effect of health publicity on plateletpheresis donation among college students in Beijing. 【Methods】 Plateletpheresis donor recruitment was carried out in a conventional way in 2016~2017 and by health publicity in 2018~2019 among college students in Beijing. The data, including the number of blood donations, blood collection units, the number of repeated donations, the rate of eligible donors and the discarding rate due to blood donation reactions, of two groups were collected and statistically analyzed. 【Results】 The number of plateletpheresis donation, the collection units of platelets and the number of repeated blood donation among college students in Beijing have increased since 2016. The rate of ineligible college students at pre-donation screening decreased from 10.97% in 2016~2017 to 8.51% in 2018~2019(P<0.05), and the discarding rate due to blood donation reactions decreased from 0.45% to 0.17%(P<0.05). Most plateletpheresis candidates failed in the blood routine testing. 【Conclusion】 Health publicity helped college students in Beijing better understand the process of plateletpheresis donation to a certain extent, which played a positive role in expanding blood donors and promoting the recruitment and retention of apheresis donors in Beijing.
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Objective To study the effect of non-nutritional sucking intervention on low birth weight infants.Methods One hundred and forty cases of low birth weight infants were randomly divided into experimental group(n=73) and conventional group (n=67).Both groups of infants were treated with enteral nutrition.The experimental group was treated with non-nutritive sucking interventions.Results The abnormality rate of QRS wave(2.74％) and heart rate (4.11％) in experimental group were significantly lower than those in the conventional group (11.94 ％,17.91 ％),the differences were statistically significant (P＜ 0.05).In the experimental group,the meconium discharge time,recovery time,nasogastric tube indwelling time and the time of intestinal nutrition reached 481.4 kJ-1 · kg-1 · d-1 were significantly lower than that of the conventional group(P＜0.05).The incidence of bloating(2.74 ％),vomiting (2.74 ％) and gastric retention (5.48 ％) in experimental group were significantly lower than than of the conventional group (13.43％,11.94％,25.37％),P＜0.05.There was no significant difference in the incidence of apnea and diarrhea between the two groups (P＞0.05).Conclusion Non-nutritional sucking intervention can effectively reduce the incidence of ECG abnormalities and feeding complications in low birth weight infants.
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Objective To investigate the diagnostic value of multiparametric MRI in early prostate cancer(PCa) based on PI-RADS version 2.Methods 27 surgically-proved early PCa patients were collected in this retrospective study.T2WI,DWI and DCE were evaluated by two blinded radiologists.By 12 sub-region classification method the possibility of the presence of cancer at each sub-region was scored according to the PI-RADS V2.The receiver operating characteristic (ROC) curve was used to analyze the diagnosic efficacy of the following 4 protocols:T2WI alone(protocol 1),T2WI+DWI(protocol 2),T2WI+DCE(protocol 3),T2WI+DWI+DCE(protocol 4).The sensitivity,specificity and accuracy for each protocol were calculated.The average scores of cancerous sub-regions and non-cancerous sub-regions were calculated and the independent sample t test was used to compare the four protocols.Results 324 sub-regions were analyzed in 27 early PCa patients and then divided into 119 cancerous sub-regions and 205 non-cancerous sub-regions,including 64 peripheral zone cancerous sub-regions and transition zone cancerous sub-regions.In protocol 1-4, the average scores of cancerous sub-regions in orderwere 3.13±1.19,3.27±1.15,3.28±1.23, 3.33±1.16,respectively.Non-cancerous sub-regions's scores in order were 1.98±0.90,1.91±0.91, 2.03±0.99,1.94±0.96 respectively and there were significant differences among each protocol (P0.05).In four protocols, the sensitivity in order were 45.40%, 56.30%, 59.70%, 61.34%, while the specificity in order were 95.10%, 96.10%, 89.80%, 96.60%, and the accuracy in order were 76.85%, 81.48%, 78.70%, 83.65%.Conclusion Multiparametric MRI can improve the diagnostic accuracy for the detection of early PCa, and T2WI+DWI+DCE is with the highest value.The PI-RADS V2 system is a better semi quantitative method for evaluation of early PCa.
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The complete nucleotide sequence of two cryptic plasmids isolated from Lactobacillus plantarum strain AS1.2986 has been determined. The smaller plasmid, designated pLP2000, encodes a 37.0kDa Rep protein and has a 17bp sequence repeated 10 times. Sequence analysis of the larger plasmid, designated pLP9000, revealed nine putative open reading frames (ORFs). Based on sequence similarity, ORF1 codes for a putative magnesium transporter protein that shows similarities to CorA from plasmid pCIS3 (Lactococcus lactis). None of the nine ORFs shows similarity to any known Rep protein. Southern blot analysis indicates these two plasmids both replicate via a rolling circle (RC) mechanism.
