RESUMO
We developed MR-dacryocystography as a non-invasive, safer imaging technique for canaliculi, the nasolacrimal duct and lacrimal sac by dropping saline solution and diluted Gd-DTPA solution into the eye. The diluted Gd-DTPA solution was found to create no local irritation in the eyes of rabbits and normal volunteers. Lacrimal sacs and ducts were well visualized in all of 10 normal volunteers by using the saline solution or the diluted Gd-DTPA solution. Canaliculi were visualized in 4-7 cases on thin-slice axial images. MR-dacryocystography was suggested to be a useful screening examination for lacrimal outflow disorders.
Assuntos
Aparelho Lacrimal/anatomia & histologia , Imageamento por Ressonância Magnética/métodos , Adulto , Animais , Feminino , Gadolínio DTPA , Humanos , Masculino , Ducto Nasolacrimal/anatomia & histologia , Coelhos , Cloreto de SódioRESUMO
A forty-year-old woman who developed brain abscess was found to Rendu-Osler-weber syndrome with multiple arteriovenous fistulas of the left lung. Therapeutic embolization of pulmonary arteriovenous fistulas was performed for the prevention against brain abscess and improvement of hypoxia.
Assuntos
Fístula Arteriovenosa/terapia , Abscesso Encefálico/terapia , Embolização Terapêutica , Artéria Pulmonar , Veias Pulmonares , Telangiectasia Hemorrágica Hereditária/terapia , Adulto , Fístula Arteriovenosa/complicações , Fístula Arteriovenosa/diagnóstico por imagem , Abscesso Encefálico/diagnóstico por imagem , Abscesso Encefálico/etiologia , Humanos , Artéria Pulmonar/diagnóstico por imagem , Veias Pulmonares/diagnóstico por imagem , Radiografia , Telangiectasia Hemorrágica Hereditária/complicações , Telangiectasia Hemorrágica Hereditária/diagnóstico por imagemRESUMO
A new embolic material has been devised to improve the therapeutic effect of ferromagnetic embolization upon tumors. Iron sponge microspheres (diameter 10-30 mu) were suspended in viscous, aqueous polysaccharide solution, dextran 40, and sodium carboxymethyl cellulose (Ferro-polysaccharide, FPS). Transcatheter embolization with FPS was performed under external magnetic control (2,800 gauss) in dog kidneys and VX2 carcinomas of rabbits, causing widespread, intraparenchymal vascular occlusion of target vessels. Neither recanalization nor collateral circulation was found to the infarcted areas, and the embolized tumors had extensive necrosis with resultant tumor regression. No significant untoward reaction or other undesirable embolization was noted serologically or histologically, even after intravenous administration of FPS. Clinical application to two patients, one with a hepatoma and the other with a renal cell carcinoma, resulted in excellent tumor infarction with no significant side effects.
