1.
Org Biomol Chem
; 9(10): 3948-53, 2011 May 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21445438
RESUMO
The partial reduction of pyrroles is not a common practice even though it offers a potential route to pyrroline building blocks, commonly used for synthesis. We have investigated the reduction of 2-acyl-N-sulfonylpyrroles and by varying the hydride source and solvent, achieved a chemoselective reduction, leading to 3-pyrrolines and alkyl pyrroles in high yield.