Adaptive Accumulation of Plantar Pressure for Ambulatory Activity Recognition and Pedestrian Identification.

In this paper, we propose a novel method for ambulatory activity recognition and pedestrian identification based on temporally adaptive weighting accumulation-based features extracted from categorical plantar pressure. The method relies on three pressure-related features, which are calculated by accumulating the pressure of the standing foot in each step over three different temporal weighting forms. In addition, we consider a feature reflecting the pressure variation. These four features characterize the standing posture in a step by differently weighting step pressure data over time. We use these features to analyze the standing foot during walking and then recognize ambulatory activities and identify pedestrians based on multilayer multiclass support vector machine classifiers. Experimental results show that the proposed method achieves 97% accuracy for the two tasks when analyzing eight consecutive steps. For faster processing, the method reaches 89.9% and 91.3% accuracy for ambulatory activity recognition and pedestrian identification considering two consecutive steps, respectively, whereas the accuracy drops to 83.3% and 82.3% when considering one step for the respective tasks. Comparative results demonstrated the high performance of the proposed method regarding accuracy and temporal sensitivity.

Factors associated with electroencephalographic and clinical remission of benign childhood epilepsy with centrotemporal spikes.

PURPOSE: Benign childhood epilepsy with centrotemporal spikes (BECTS) is strongly related to age, both to age at the time of seizure onset and to age at remission. However, the age of remission varies. The present study analyzed factors associated with remission of BECTS. METHODS: Sixty-nine children with BECTS were retrospectively analyzed. Thirty-eight (55.1%) were boys and 31 (44.9%) were girls. Mean age at seizure onset was 86.36 ±â€¯24.55 months (range: 41-151 months). RESULTS: The mean age at the time of EEG improvement or remission was 138.31 ±â€¯19.71 months. Of the 69 patients, 36 (52.2%) exhibited electroencephalography (EEG) improvement or remission before age 11.5 years, whereas 33 (47.8%) showed later improvement or remission. The two groups differed significantly in age at seizure onset. When patients were divided into groups using an age cutoff for last seizure of 9 years, the two groups differed significantly in age at seizure onset. CONCLUSIONS: The most important predictor of early BECTS remission is age at seizure onset.

Short-Term Outcome of Intravenous Methylprednisolone Pulse Therapy in Patients With Infantile Spasms.

BACKGROUND: Many studies advocate hormonal treatments including high-dose oral prednisolone as an effective treatment for epileptic spasms. However, little is known about the effects of intravenous methylprednisolone pulse therapy on infantile spasms. We investigated the short-term response to intravenous methylprednisolone pulse therapy for the treatment of infantile spasms. METHODS: Patients with newly diagnosed infantile spasms and hypsarrhythmia on electroencephalography (EEG) at two tertiary centers in Korea were included. Patients received intravenous infusions of 30 mg/kg/day methylprednisolone for three days with tapering doses of oral prednisolone for two to four weeks for the treatment of infantile spasms. Response to methylprednisolone pulse therapy was evaluated by seizure frequency and follow-up EEG within three weeks. RESULTS: Fourteen patients were sudied. The mean age at the onset of spasms was 7.0 months (range, 2.0 to 11.0 months). Etiological factors included structural abnormalities (N = 11), chromosomal anomaly (N = 1), and unknown (N = 2). Nine of 14 participants (64.3%) demonstrated complete freedom from spasm and resolution of hypsarrhythmia on EEG within 3 weeks; however, only five of nine responders (55.5%) remained free of spasms after the discontinuation of oral steroids. Adverse effects, including irritability or infection, were observed in four patients but were tolerable in all. CONCLUSIONS: Short-term methylprednisolone pulse therapy for the treatment of infantile spasms or hypsarrhythmia demonstrated rapid improvement in EEG and cessation of spasms without serious adverse effects. Further studies are needed to determine the long-term effects of spasm control.