BCG(Bacillus Calmette-Guerin) for Superficial Transitional Cell Carcinoma of the Bladder: A Preliminary Report(I) / 대한비뇨기과학회지

Tice-Chicago strain bacillus Calmette-Guerin was used to treat superficial transitional cell carcinoma of the bladder in 11 patients. The treatment regimen of 120mg. Tice-Chicago strain bacillus Calmette-Guerin weekly for 6 weeks and then monthly for 3 months was well tolerated. Side effects during or shortly after treatment were minor and self-limiting in the majority of patients (fever, bladder irritability and hematuria). Although the findings are still preliminary, they appear to hold promise of a new therapeutic approach to the treatment of a group of carcinoma of the bladder for which effective therapy is still lacking in this country.

Metastatic Prostatic Adenocarcinoma: A Clinical Review of 21 Cases / 대한비뇨기과학회지

Herein we analyze retrospectively 21 patients with stage D prostatic adenocarcinoma admitted to our hospital during the period from January 1980 through December 1985. Of the 40 patients who had prostatic adenocarcinoma, 21 (50%) patients were classified as stage D. The presenting symptoms were prostatism (10), urinary retention (6), gross hematuria (2), lumbago (2) and pathologic bone fracture (1). Of the 21 patients, 15 (71%,) patients had elevated enzymatic acid phosphatase levels and 7 patients had distant metastases. Stage D prostatic carcinoma was subclassified as stage D

CISCA Combination Chemotherapy in Advanced Bladder Cancer / 대한비뇨기과학회지

The management of the patient with recurrent local of disseminated bladder cancer presents a difficult problem. In the majority of these patients an operation or radiation therapy is of no value. Because none of the single agent chemotherapy seems to be capable of achieving an objective response rate greater than 50 percent and because complete responses are rare, combination chemotherapy trials have been developed. In l977 Sternberg et al reports 83 percent response rate (CR: 8%, PR: 75%) with CISCA combination chemotherapy (cis-platinum, cyclophosphamide, adriamycin) in advanced urinary tract carcinoma. Other similar studies have shown various results ranging from 43 to 82 percent response rate in advanced bladder cancer. Herein, we report 3 cases of CISCA combination chemotherapy in far advanced bladder cancer, which had measurable metastatic lesions enough to evaluate the objective response of chemotherapy.

XX-Male Syndrome: A Case Report / 대한비뇨기과학회지

The XX-male or sex reversal syndrome is a rare entity, which a is phenotypic man with a 46, XX female karyotype. Since it was first reported by la Chapelle and associates in 1964, more than 150 XX males have been reported. Recently we experienced a 18-year-old XX-male with gynecomastia and hypospadias. Clinical, endocrinological and genetically studies were presented and theories regarding the etiology of the XX-male syndrome were discussed with review of literatures.

A Case of Systemic Chemetherapy in Advanced Seminoma / 대한비뇨기과학회지

Seminoma is one of the most radiosensitive solid tumors. However, the survival of patients with clinically advanced stages B3 and C disease is poor. Most of the failures of treatment in advanced stage seminoma, however, come from systemic diseases outside radiation fields or are secondary to unrecognized non-seminomatous elements. Therefore adjuvant systemic chemotherapy is essential for proper treatment of three patients. Recently we experienced a case of advanced stage seminoma treated with radical inguinal orchiectomy followed by systemic chemotherapy with good result.

Endoscopic Internal Urethrotomy in the Management of Urethral Strictures / 대한비뇨기과학회지

Endoscopic internal urethrotomy was done on 25 patients with urethral strictures. Of these patients 24 have been followed for 3 to 22 months. Satisfactory results were obtained in 56 per cent of the patients. The overall morbidity rate was 18 per cent, but potency was not endangered. Patients with long and multiple strictures caused by trauma had unstatisfactory results, while the duration of catheterization did not affect the results. Most recurrent strictures manifested themselves within 3 months. Despite these less successful results endoscopic internal urethrotomy, which is usually performed at hand, should be tried as a primary procedure except for complete ruptures or destruction of segments of the urethra, in which cases open reconstructive perineal urethroplasty is our procedure of choice.