RESUMO
BACKGROUND: The differential diagnosis of common pigmented skin lesions is important in cosmetic dermatology. The computer aided image analysis would be a potent ancillary diagnostic tool when patients are hesitant to undergo a skin biopsy. OBJECTIVE: We investigated the numerical parameters discriminating each pigmented skin lesion from another with statistical significance. METHODS: For each of the five magnified digital images containing clinically diagnosed nevus, lentigo and seborrheic keratosis, a total of 23 parameters describing the morphological, color, texture and topological features were calculated with the aid of a self-developed image analysis software. A novel concept of concentricity was proposed, which represents how closely the color segmentation resembles a concentric circle. RESULTS: Morphologically, seborrheic keratosis was bigger and spikier than nevus and lentigo. The color histogram revealed that nevus was the darkest and had the widest variation in tone. In the aspect of texture, the surface of the nevus showed the highest contrast and correlation. Finally, the color segmented pattern of the nevus and lentigo was far more concentric than that of seborrheic keratosis. CONCLUSION: We found that the subtle distinctions between nevus, lentigo and seborrheic keratosis, which are likely to be unrecognized by ocular inspection, are well emphasized and detected with the aid of software.
Assuntos
Humanos , Bioengenharia , Cosméticos , Dermatologia , Diagnóstico Diferencial , Processamento de Imagem Assistida por Computador , Ceratose Seborreica , Lentigo , Nevo , PeleRESUMO
BACKGROUND: The differential diagnosis of common pigmented skin lesions is important in cosmetic dermatology. The computer aided image analysis would be a potent ancillary diagnostic tool when patients are hesitant to undergo a skin biopsy. OBJECTIVE: We investigated the numerical parameters discriminating each pigmented skin lesion from another with statistical significance. METHODS: For each of the five magnified digital images containing clinically diagnosed nevus, lentigo and seborrheic keratosis, a total of 23 parameters describing the morphological, color, texture and topological features were calculated with the aid of a self-developed image analysis software. A novel concept of concentricity was proposed, which represents how closely the color segmentation resembles a concentric circle. RESULTS: Morphologically, seborrheic keratosis was bigger and spikier than nevus and lentigo. The color histogram revealed that nevus was the darkest and had the widest variation in tone. In the aspect of texture, the surface of the nevus showed the highest contrast and correlation. Finally, the color segmented pattern of the nevus and lentigo was far more concentric than that of seborrheic keratosis. CONCLUSION: We found that the subtle distinctions between nevus, lentigo and seborrheic keratosis, which are likely to be unrecognized by ocular inspection, are well emphasized and detected with the aid of software.
Assuntos
Humanos , Bioengenharia , Cosméticos , Dermatologia , Diagnóstico Diferencial , Processamento de Imagem Assistida por Computador , Ceratose Seborreica , Lentigo , Nevo , PeleRESUMO
No abstract available.
Assuntos
Malformações Arteriovenosas , Embolização Terapêutica , Telangiectasia Hemorrágica HereditáriaRESUMO
Therapeutic options for infantile hemangioma are limited. The nonselective beta-adrenergic receptor antagonist propranolol is an effective therapy for infantile hemangiomas. However, systemic propranolol carries a risk of serious side effects, including bradycardia, hypoglycemia, arrhythmias, hypotension and bronchospasm. Recently, treatment of infantile hemangioma with topical timolol (nonselective beta-blocker similar to propranolol) has been reported. We treated successfully the perineal ulcerative hemangioma with topical timolol. We believe that timolol is a safe and effective topical agent and should be strongly considered as one of good therapeutic options for hemagnioma.
Assuntos
Arritmias Cardíacas , Bradicardia , Espasmo Brônquico , Hemangioma , Hipoglicemia , Hipotensão , Propranolol , Timolol , ÚlceraRESUMO
Therapeutic options for infantile hemangioma are limited. The nonselective beta-adrenergic receptor antagonist propranolol is an effective therapy for infantile hemangiomas. However, systemic propranolol carries a risk of serious side effects, including bradycardia, hypoglycemia, arrhythmias, hypotension and bronchospasm. Recently, treatment of infantile hemangioma with topical timolol (nonselective beta-blocker similar to propranolol) has been reported. We treated successfully the perineal ulcerative hemangioma with topical timolol. We believe that timolol is a safe and effective topical agent and should be strongly considered as one of good therapeutic options for hemagnioma.
Assuntos
Arritmias Cardíacas , Bradicardia , Espasmo Brônquico , Hemangioma , Hipoglicemia , Hipotensão , Propranolol , Timolol , ÚlceraRESUMO
Febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta (PLEVA), or febrile ulcerative Mucha-Haberman disease (FUMHD) is very rare, but potentially lethal variants of PLEVA. This subtype is characterized by rapidly progressive ulceronecrotic lesions and systemic manifestations, such as high fever, gastrointestinal, neurological, cardiologic and pulmonary involvement, and rheumatologic manifestations. Several treatments with variable response have been challenged, such as systemic steroid, antibiotics, methotrexate, dapsone, cyclosporine and ultraviolet therapy. But there is no standard therapy for FUMHD to date. We report a 59-year-old woman with FUMHD, who recurred after discontinuation of systemic steroid, but successfully treated with oral cyclosporine.
Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Antibacterianos , Ciclosporina , Dapsona , Febre , Metotrexato , Pitiríase , Pitiríase Liquenoide , Úlcera , Terapia UltravioletaRESUMO
BACKGROUND: Tinea corporis includes all superficial dermatophyte infections of the skin other than those involving the scalp, beard, hands, feet, and groin. OBJECTIVE: The purpose of this study is to evaluate the clinical features of tinea corporis. METHOD: Clinical findings of tinea corporis diagnosed at Boramae Medical Center in the last 10 years were analyzed retrospectively. RESULTS: For the 10-year study, a total of 422 patients were analyzed. Male-to-female ratio was 0.8:1, and patients were diagnosed most often in their twenties (26.5%). Average duration of the lesions before visiting our clinic was 4.9 months. Skin lesions appeared most frequently in the summer (45.3%). Clinical appearance was most often annular (83.9%), followed by eczematous annular (13.7%) and plaque type (2.4%). Average number of lesions was 4. Lesions over 5 cm in longest diameter accounted for 47.2%; however, when occurring in the face they were significantly less frequent (4.9%). Lesions developed in unexposed areas in 60.4%, most commonly on the chest, followed by back and buttock. In 60% of patients, concurrent dermatophytosis of other regions were present, most commonly tinea pedis (58%), followed by tinea unguium (31.2%). History of prior contact with animal was in 12.3% of total but significantly higher in facial lesions (54.7%). CONCLUSION: Dermatologists should always examine the feet and toenails of patients with suspected tinea corporis since over half of these patients harbor fungal infection in the feet.
Assuntos
Animais , Humanos , Arthrodermataceae , Nádegas , Pé , Mãos , Unhas , Onicomicose , Couro Cabeludo , Pele , Tórax , Tinha , Tinha dos PésRESUMO
BACKGROUND: Physiological parameters of the skin measured by non-invasive methods have been considerably developed. It is known that there are some differences in physiologic parameters between different races. OBJECTIVE: The purpose of this study is to understand the differences between the races. METHODS: A total of 757 Mongolian participated in this study. All subjects had no major history of skin diseases requiring medical treatment. Several instruments were used such as Sebumeter, Corneometer, Mexameter for measuring sebum excretion rate, values of capacitance, melanin index and erythema index respectively. These were measured on various areas of the skin such as cheek, forehead, palm, outer arm, inner arm, back and buttock. RESULTS: The sebum excretion rates showed higher in males than in females on the cheek and forehead in Mongolian. However, they showed higher in the females on the palm. There were good correlation between the skin sebum level and the capacitance in males and females. The melanin index and erythema index showed higher in males than in females at all sites. When we compared this with the data published in other countries, many data were similar to Korean rather than a western country's. However, the capacitance data were lower than those of Korean. CONCLUSION: Although, this study has some limit for direct comparison between each race, our results can be used as basic data for the comparison between Mongolian and other races in the future.
Assuntos
Feminino , Humanos , Masculino , Braço , Bioengenharia , Bochecha , Grupos Raciais , Eritema , Testa , Melaninas , Sebo , Pele , DermatopatiasRESUMO
BACKGROUND: Patients with severe atopic dermatitis (AD) can benefit from cyclosporin (CSA) treatment. Some studies reported that CSA can cause infectious diseases as side effects. OBJECTIVE: To investigate the possible association of CSA treatment in AD patients with infectious diseases. METHODS: We performed a case-controled study on 202 patients with AD, 101 of whom were taking CSA and 101 who were not. Retrospective medical record review was held, and the incidence of infectious disease in both groups was compared. RESULTS: The total number of infectious diseases in the CSA group was slightly lower than in control group but that was not statistically significant. Similarly, the incidence density was almost the same in the two groups. In both groups, eczema herpeticum was the most common infection. CONCLUSION: Our results suggest that CSA therapy in AD does not increase the incidence of infectious disease.
