RESUMO
Two new phthalide dimers, namely chuanxiongnolide A (1) and chuanxiongnolide B (2), along with eleven known phthalides and derivatives ( 3 - 13), were isolated from the roots of Ligusticum chuanxiong Hort. (Umbelliferae). The chemical structures of the new compounds were established by HR-ESI-MS, 1D- and 2D-NMR spectroscopic analysis, whilst the relative stereochemistry of 1 was confirmed by X-ray crystallographic data.
Assuntos
Benzofuranos/química , Benzofuranos/isolamento & purificação , Ligusticum/química , Cristalografia por Raios X , Análise EspectralRESUMO
Three new diterpene alkaloids, 16,17-dihydro-12 beta,16 beta-epoxynapelline (1), N-deethyl- N-methyl-12-epi-napelline (2) and 11- epi-16 alpha,17-dihydroxylepenine (3), along with twenty-six known alkaloids (4 - 29) were isolated from the roots of Aconitum nagarum var. lasiandrum. The chemical structures of the new compounds were established by HR-MS as well as 1D- and 2D-NMR spectroscopic analysis. The absolute stereochemistry of 1 was confirmed by X-ray crystallography.
Assuntos
Aconitum/química , Diterpenos/química , Medicamentos de Ervas Chinesas/química , Alcaloides/química , Alcaloides/isolamento & purificação , Diterpenos/isolamento & purificação , Estrutura Molecular , Ressonância Magnética Nuclear Biomolecular , Raízes de Plantas/químicaRESUMO
The title compound, 5-hydroxy-4',7-dimethoxyisoflavone, C17H14O5, is composed of a benzopyranone moiety, a phenyl moiety and two methoxy groups. The benzopyranone ring is not coplanar with the phenyl ring, the dihedral angle between them being 56.28 (3) degrees. The two methoxy groups are nearly coplanar with their corresponding rings, having C-C-O-C torsion angles of 2.9 (2) and 5.9 (2) degrees . The molecules are linked by C-H...O hydrogen bonds into sheets containing classical centrosymmetric R2(2) (8) rings. The sheets are further linked by aromatic pi-pi stacking interactions and C-H...O hydrogen bonds into a supramolecular structure.
