1.
J Org Chem
; 76(17): 7216-21, 2011 Sep 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21800844
RESUMO
The marine natural product 16-deacetoxy-12-epi-scalarafuranacetate, isolated from Spongua officinalis , was synthesized in 18 linear steps, starting from (-)-sclareol, with high stereoselectivity and an overall yield of 6.1%. The intermediate 16-deacetoxy-12-epi-scalarafuran could be easily transformed into a series of natural scalarane sesterterpenoids in a few steps.