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1.
Acta Gastroenterol Belg ; 81(2): 333-335, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30024708

RESUMO

Organophosphate(OPH) compounds are cholinesteraseinhibiting chemicals used as pesticide. Pancreatitis secondary to malathion toxicity is rare and toxic hepatitis has been reported in only one case. In this paper, we report the case of the combination of acute pancreatitis and toxic hepatitis, which developed in a 30-year old farm worker and the mechanism is discussed in this first report of its kind. Awareness of this complication should prompt earlier investigation because early diagnosis coupled with timely therapeutic measures may improve patient prognosis.


Assuntos
Doença Hepática Induzida por Substâncias e Drogas/etiologia , Malation/toxicidade , Pancreatite/induzido quimicamente , Adulto , Doença Hepática Induzida por Substâncias e Drogas/terapia , Tratamento Conservador , Fazendeiros , Humanos , Masculino , Pancreatite/terapia
2.
Mater Sci Eng C Mater Biol Appl ; 75: 425-432, 2017 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-28415481

RESUMO

An interpenetrated polymer network (IPN) poly(NIPAAm-co-AAc) hydrogel was synthesized by two polymerization method: emulsion and solution polymerization. The pH- and temperature-sensitive hydrogel was loaded by swelling with riboflavin drug, a B2 vitamin. The release of riboflavin as a function of time has been achieved under different pH and temperature environments. The determination of experimental conditions and the analysis of drug delivery results were achieved using response surface methodology (RSM). In this work, artificial neural networks (ANNs) in MATLAB were also used to model the release data. The predictions from the ANN model, which associated input variables, produced results showing good agreement with experimental data compared to the RSM results.


Assuntos
Resinas Acrílicas , Hidrogéis , Modelos Químicos , Rede Nervosa , Riboflavina , Resinas Acrílicas/química , Resinas Acrílicas/farmacocinética , Preparações de Ação Retardada/química , Preparações de Ação Retardada/farmacocinética , Temperatura Alta , Humanos , Hidrogéis/química , Hidrogéis/farmacocinética , Concentração de Íons de Hidrogênio , Riboflavina/química , Riboflavina/farmacocinética
3.
Radiat Prot Dosimetry ; 168(1): 134-47, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25693600

RESUMO

The present study analyses the electric field radiating from the GSM/UMTS base stations located in central Malatya, a densely populated urban area in Turkey. The authors have conducted both instant and continuous measurements of high-frequency electromagnetic fields throughout their research by using non-ionising radiation-monitoring networks. Over 15,000 instant and 13,000,000 continuous measurements were taken throughout the process. The authors have found that the normal electric field radiation can increase ∼25% during daytime, depending on mobile communication traffic. The authors' research work has also demonstrated the fact that the electric field intensity values can be modelled for each hour, day or week with the results obtained from continuous measurements. The authors have developed an estimation model based on these values, including mobile communication traffic (Erlang) values obtained from mobile phone base stations and the temperature and humidity values in the environment. The authors believe that their proposed artificial neural network model and multivariable least-squares regression analysis will help predict the electric field intensity in an environment in advance.


Assuntos
Cidades , Radiação Eletromagnética , Exposição Ambiental/análise , Monitoramento de Radiação/métodos , Algoritmos , Telefone Celular , Comunicação , Campos Eletromagnéticos , Análise dos Mínimos Quadrados , Modelos Estatísticos , Análise Multivariada , Redes Neurais de Computação , Ondas de Rádio , Turquia
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