Effects of a nutrient-dense formula compared with a post-discharge formula on post-discharge growth of preterm very low birth weight infants with extrauterine growth retardation: a multicentre randomised study in China.

BACKGROUND: Post-discharge optimal growth and nutritional intake have beneficial effects for neurodevelopment in preterm very low birth weight infants (VLBWIs) with extrauterine growth retardation (EUGR). The present study aimed to compare the effects of a nutrient-dense formula (NDF) to a post-discharge formula (PDF) on post-discharge growth of preterm VLBWIs with EUGR. METHODS: Forty-eight preterm VLBWIs with EUGR at discharge were randomised to receive NDF (100 kcal per 100 mL; 2.6 g protein per 100 mL) or PDF (74 kcal per 100 mL; 1.95 g protein per 100 mL) for 1-6 months until body weight reached the 50th percentile on growth charts with corrected age. Volume, nutrient intake, anthropometry and biochemistry data were collected. RESULTS: Volume intake was lower in the NDF group than the PDF group during the first 2 months of feeding (P = 0.039 and 0.018, respectively).There were no significant differences in volume intake during months 2-6 of feeding. Energy, protein, carbohydrate and fat intake were higher in the NDF group during months 1-6 of feeding. There were no significant differences in weight, length, and head circumference Z-scores during months 1-6 between the two groups. The △length Z-score from discharge to month 6 was significantly higher in the NDF group than the PDF group (P = 0.043). No differences existed between the two groups with respect to biochemistry. CONCLUSIONS: After discharge, preterm VLBWIs with EUGR fed a NDF gain anthropometric parameter Z-scores similar to those for a PDF within 6 months of follow-up. A NDF leading to gain in length requires further follow-up.

Isolated metal- backed patellar component revision following total knee arthroplasty / 中华骨科杂志

Objective To analyse the reasons of failure of metal- backed patellar component and observe the clinical outcome of the revision procedure. Methods Thirty isolated patellar revision for failed metal- backed patellar components following total knee arthroplasty in 22 patients were reviewed. All had similar total condylar knee prosthesis inserted with retention of the posterior cruciate ligament and resurfacing of the patella. There were 4 males and 18 females. Knee Society Score rating system was used for the final evaluation. Results In average the failure occurred in 62.3 months (ranged from 26 to 96 months). The majority of patients presented with metallic crepitus(80％ ) and pain of the knee(70％ ). At surgery, full thickness polyethylene wear exposing the metal- backing was present in 76.7％ with surface damage of the femoral components in 36.7％ . There was tilting of patella in 9 knees and dislocation of patella in 2 knees. All 30 knees underwent successful isolated patellar component revision with cemented polyethylene patellar buttons. Final follow- up averaged 42.5 months, all manifestations were reported significant improvement in 22 patients. The average knee score improved from 73 points(ranged from 27 to 88) pre- revision to 87 points(ranged from 60 to 100) at the final follow- up. Conclusion Resurfacing of the patella in total knee arthroplasty with metal- backed patellar components carries a significant risk of early failure. Malalignment and maltracking of patella may be a predisposing factor to early failure in metal- backed patellar components.