Sublethal Effects of Cadmium on the Osmoregulatory and Acid-Base Parameters of Tilapia (Oreochromis niloticus) at Various Times.

Background: Cadmium (Cd) can contaminate aquatic environments as a result of anthropogenic activity. Cd accumulates quickly in the tissues of fish and has the potential to affect their physiology, including osmoregulation and acid-base balance. Therefore, the purpose of this study was to examine the sublethal effects of Cd on the osmoregulation and acid-base balance of tilapia Oreochromis niloticus at different times. Methods: Fish were exposed to sublethal concentrations of Cd (1 and 2 mg/L) for 4 and 15 days. At the end of the experiment, fish were collected from each treatment to examine the levels of Cd and carbonic anhydrase (CA) in the gills, plasma osmolality, ions, blood pH, pCO2, pO2, and hematological parameters. Results: Cd concentrations in gills rose with increasing Cd concentrations in the medium and exposure time. Cd inhibited respiration by generating metabolic acidosis, decreasing gill CA, reducing pO2, plasma osmolality, Cl-, and K+, particularly at 2 mg/L for 4 days and 1 and 2 mg/L for 15 days. Red blood cell (RBC), hemoglobin (Hb), and hematocrit (Ht) levels decreased as Cd levels in water and exposure duration increased. Conclusion: Cd inhibits respiration, lowers RCB, Hb, and Ht levels and decreases ionic and osmotic regulation. All of these impairments can limit a fish's ability to provide appropriate oxygen to its cells, hence diminishing its physical activity and productivity.

Health risk assessment of metals in mud crab (Scylla serrata) from the East Java Estuaries of Indonesia.

Metals accumulating in mud crab from Indonesia's East Java estuaries have been assessed for potential health effects. Mud crabs from the Solo River estuary (JS) had the highest levels of all metals tested when compared to mud crabs from the Brantas River estuary (MS) and the Banyuwangi coastal area (BS). Metal accumulation in mud crabs occurred in the following order: Zn > Cu > Cr > Pb > Cd > Hg. The estimated weekly intake values for all metals from all stations were less than the provisional tolerable weekly intake requirement. Similarly, all metal target hazard quotient values from all stations were less than one, suggesting that all metals were within the allowable intake limit. The target cancer risk values for Cd and Cr, on the other hand, were somewhat higher than 10-4, indicating that they were dangerous for human ingestion and possibly linked to a risk associated with carcinogenic agent exposure over a lifetime.