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Chinese Pharmacological Bulletin ; (12): 1320-1324, 2023.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-1013755

RESUMO

Aim To build the model of the gene FKBP38(FK506 binding protein 38)conditional knock out in uterus and then investigate the effect on endometrial precancerous lesions and the underlying mechanism.Methods Transgenic mice whose FKBP38 gene was flanked with loxP were constructed by embryo microinjection. The conditional knockout of FKBP38 was obtained by breeding mice harboring two loxP sites in FKBP38(FKBP38

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