RESUMO
Chronic myelomonocytic leukemia has been associated with various nonspecific cutaneous manifestations. Rarely has the leucaemia been reported to directly affect the skin. We present a case of 53-year old man with CMML who showed neoplastic cutaneous lesions. The occurrence of these lesions may be the presenting feature of the disease or may herald its progression to acute leukemia. Early diagnosis have therapeutic and prognostic significance.
Assuntos
Leucemia Mielomonocítica Crônica/patologia , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/secundário , Progressão da Doença , Humanos , Masculino , Pessoa de Meia-Idade , PrognósticoRESUMO
Prognostication of the course of atopic dermatitis (AD) is of special importance in prophylaxis of this disease. The aim of the study was to describe the AD minor feature sets, according to Hanifin and Rajka, on the basis of which one can predict the occurrence of extensive skin lesions, allergic rhinitis, atopic bronchial asthma, cataracts, hand and/or foot dermatitis, food intolerance, urticaria and elevated IgE serum in AD patients. Two-hundred-fifty-four patients were included in the study. Minor feature sets of prognostic value were selected using the MANOVA method in conjunction with the discriminant analysis. On the basis of the above sets, one can predict: involvement of more than 60% of body surface, occurrence of allergic rhinitis, elevated serum IgE, cataracts, atopic bronchial asthma, food intolerance and urticaria with the probability ratio of 90.8%, 82.8%, 79.9%, 78.4%, 77.3%, 77.1% and 76.1% respectively. In the examined group, no association was found between hand and/or foot dermatitis and the tendency towards skin infection.
Assuntos
Dermatite Atópica/complicações , Dermatite Atópica/diagnóstico , Adolescente , Adulto , Análise de Variância , Dermatite Atópica/classificação , Feminino , Humanos , Imunoglobulina E/sangue , Masculino , Pessoa de Meia-Idade , Pescoço/patologia , Prognóstico , Prurido/complicações , Rinite Alérgica Perene/complicações , Sensibilidade e Especificidade , Dermatopatias/complicaçõesAssuntos
Artrite Infecciosa/diagnóstico , Grupo Borrelia Burgdorferi/imunologia , Eritema Migrans Crônico/diagnóstico , Doença de Lyme/diagnóstico , Meningoencefalite/diagnóstico , Adulto , Idoso , Anticorpos Antibacterianos/análise , Anticorpos Antibacterianos/imunologia , Antígenos de Bactérias/imunologia , Artrite Infecciosa/etiologia , Artrite Infecciosa/imunologia , Western Blotting/métodos , Eritema Migrans Crônico/etiologia , Eritema Migrans Crônico/imunologia , Reações Falso-Negativas , Fluorimunoensaio/métodos , Humanos , Imunoglobulina G/análise , Imunoglobulina G/imunologia , Imunoglobulina M/análise , Imunoglobulina M/imunologia , Doença de Lyme/complicações , Doença de Lyme/imunologia , Meningoencefalite/etiologia , Meningoencefalite/imunologia , Pessoa de Meia-Idade , PolôniaRESUMO
In 79 males aged 19-21 years with acute and chronic urticaria living under similar conditions the levels were determined of total IgE (FIST test) and specific IgE (FAST test) against the most frequent inhaled and food allergens. Statistically significant rise of the mean value of total IgE was noted in both groups of patients. In acute urticaria increased concentration of specific IgE against inhaled allergens was significantly more common.
