RESUMO
Morphological investigation for studying of a local impact on the tissues, localized in the antiseptic textile implantation zone, was conducted. The textile was impregnated by composition of decametoxine with modified polysaccharides. Basing on the investigation result there was established the absence of a toxic impact of antiseptic medical textile on the macroorganism tissues, the regenerative processes course, the wounds epithelization, antioedematous and anti-inflammatory effects.
Assuntos
Anti-Infecciosos Locais/farmacologia , Compostos de Decametônio/farmacologia , Suturas , Cicatrização/efeitos dos fármacos , Ferimentos Penetrantes/cirurgia , Animais , Fibroblastos/efeitos dos fármacos , Linfócitos/efeitos dos fármacos , Macrófagos/efeitos dos fármacos , Masculino , Monócitos/efeitos dos fármacos , Ratos , TêxteisRESUMO
Antimicrobial properties of a composite based on decamethoxine and modified polysaccharides (carboxymethylamylum, oxyethyl-cellulose) were studied. The composite was shown to have high antimicrobial activity against grampositive and gramnegative bacteria under different conditions of the experiment.
