Assuntos
Perna (Membro)/fisiopatologia , Linfoma Difuso de Grandes Células B/diagnóstico , Linfoma Difuso de Grandes Células B/tratamento farmacológico , Linfoma Difuso de Grandes Células B/fisiopatologia , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/tratamento farmacológico , Neoplasias Cutâneas/fisiopatologia , Idoso de 80 Anos ou mais , Antibióticos Antineoplásicos/uso terapêutico , Antineoplásicos Alquilantes/uso terapêutico , Antineoplásicos Imunológicos/uso terapêutico , Antineoplásicos Fitogênicos/uso terapêutico , Ciclofosfamida/uso terapêutico , Doxorrubicina/uso terapêutico , Feminino , Humanos , Rituximab/uso terapêutico , Resultado do Tratamento , Vincristina/uso terapêuticoRESUMO
BACKGROUND: Chronic hand eczema is defined as a persistent (>6 months' duration) noninfectious skin inflammation of the hands. It is twice as common in women as men. Although genetic factors have been considered, greater exposure of women to wet work, such as housework, is assumed to be the most likely explanation. It has been debated whether lifestyle factors may be associated with chronic hand eczema. OBJECTIVE: The objective of this study was to evaluate the influence of cigarette smoking on housewives for the development of chronic hand eczema. METHODS: We analyzed 516 housewives 18 years or older. Two hundred fourteen were affected by chronic hand eczema, and 302 were control subjects. Both patients and control subjects were divided into 2 subgroups, smokers and nonsmokers. An anonymous questionnaire was submitted to each woman. CONCLUSIONS: No significant differences emerged between "smokers" and "nonsmokers" concerning the incidence of chronic hand eczema. In addition, the smokers were mainly affected by a milder ("almost clear") form of the disease. On the other hand, "severe" forms of chronic hand eczema might be more frequent in nonsmokers when compared with smokers. This study suggests that smoking is not associated with onset of chronic hand eczema, but with less severe chronic hand eczema.
Assuntos
Eczema/etiologia , Dermatoses da Mão/etiologia , Zeladoria , Fumar/efeitos adversos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Doença Crônica , Eczema/epidemiologia , Feminino , Dermatoses da Mão/epidemiologia , Humanos , Incidência , Pessoa de Meia-Idade , Fumar/epidemiologia , Inquéritos e Questionários , Adulto JovemAssuntos
Dermatite Alérgica de Contato/diagnóstico , Hipersensibilidade a Drogas/diagnóstico , Heparina/efeitos adversos , Testes do Emplastro/métodos , Administração Tópica , Adulto , Alérgenos/administração & dosagem , Dermatite Alérgica de Contato/etiologia , Feminino , Géis/efeitos adversos , Hematoma/tratamento farmacológico , Humanos , Medição de Risco/métodosRESUMO
The contact with a jellyfish is usually followed by acute inflammatory lesions, characterized by erythema, swelling, vesicles, and bullae, accompanied by burning and pain sensation. The pathogenesis is due to the direct toxic effect of the fluid contained in jellyfish tentacles. Sometimes, jellyfish may induce delayed cutaneous lesions. Delayed cutaneous reaction to jellyfish represents a clinical entity where eczematous lesions develop after days or months after contact with the invertebrate. We report the case of a patient with a delayed and persistent skin reaction due to jellyfish envenomation successfully treated with pimecrolimus.
