RESUMO
Treatment failure is a serious problem facing some national tuberculosis (TB) control programmes. Irregularity of treatment is a factor that can lead to treatment failure. A case-control study was carried out in TB centres in Egypt during April 2001-December 2002 aimed at investigating the predictors of treatment failure. We interviewed 119 people with treatment failure and an equal number of cured cases (controls) and their families regarding sociodemographic characteristics, information about TB, information about drugs, treatment compliance, family support and patient-family interaction. Significant risk factors for treatment failure were non-compliance to treatment, deficient health education to the patient, poor patient knowledge regarding the disease and diabetes mellitus as co-morbid condition.
Assuntos
Antituberculosos/uso terapêutico , Terapia Diretamente Observada , Tuberculose/tratamento farmacológico , Adulto , Estudos de Casos e Controles , Comorbidade , Complicações do Diabetes/complicações , Complicações do Diabetes/epidemiologia , Terapia Diretamente Observada/métodos , Terapia Diretamente Observada/psicologia , Escolaridade , Egito/epidemiologia , Família/psicologia , Feminino , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Cooperação do Paciente/psicologia , Educação de Pacientes como Assunto/normas , Valor Preditivo dos Testes , Avaliação de Programas e Projetos de Saúde , Fatores de Risco , Apoio Social , Fatores Socioeconômicos , Inquéritos e Questionários , Falha de Tratamento , Tuberculose/complicações , Tuberculose/epidemiologia , Tuberculose/psicologiaRESUMO
Treatment failure is a serious problem facing some national tuberculosis [TB] control programmes. Irregularity of treatment is a factor that can lead to treatment failure. A case-control study was carried out in TB centres in Egypt during April 2001-December 2002 aimed at investigating the predictors of treatment failure. We interviewed 119 people with treatment failure and an equal number of cured cases [controls] and their families regarding sociodemographic characteristics, information about TB, information about drugs, treatment compliance, family support and patient-family interaction. Significant risk factors for treatment failure were non-compliance to treatment, deficient health education to the patient, poor patient knowledge regarding the disease and diabetes mellitus as co-morbid condition
